Low kwayoyin nauyi heparins: kwayoyi, alamomi ga yin amfani da

Far da thrombosis da thromboembolic abubuwan ne ba tare da anticoagulants, wanda sun hada da low kwayoyin nauyi heparins. Wadannan abubuwa a cikin abun da ke ciki na magunguna canza jini clotting, game da shi tanadi patency.

Iri na kai tsaye anticoagulants

La'akari da tsarin ba da sakamakon antithrombotic mahadi iya lura da cewa su ne kai tsaye da kuma kai tsaye ba mataki. Da aka fi amfani da farko rukuni na abubuwa.

Anticoagulants tasiri kai tsaye a kan tsarin kasu kashi low kwayoyin nauyi heparins da unfractionated. Su kuma iya zama kai tsaye thrombin hanawa, shi ne yadda, misali, hirudin.

Low kwayoyin nauyi heparins Feature

Su daban kira fractionated mahadi wanda talakawan kwayoyin nauyi jeri daga 4000 zuwa 6000 daltons. Da ayyukan suna da alaka da wani kai tsaye ba hanawa na samuwar da kuma ayyuka na enzyme thrombin. Irin wannan sakamako heparin exerts a kan jini coagulation factor Xa. A sakamakon haka ne wani anticoagulant da antithrombotic sakamako.

Low kwayoyin nauyi heparins aka samu daga unfractionated abubuwa ware daga alade hanji epithelium, a lokacin aiwatar da sinadaran ko enzymatic depolymerization. A sakamakon wannan dauki polysaccharide sarkar ne taqaitaccen da kashi daya cikin uku na asalin tsawon, wanda taimaka wajen rage da anticoagulant kwayoyin.

Akwai daban-daban low kwayoyin nauyi heparins, kuma wannan rarrabuwa ta dogara ne a kan hanyoyin da samun gishiri-dauke da mahadi.

bayar

Su formulations ne injectable mafita ga subcutaneous ko igiyar jini gwamnati. Suna kullum cushe a ampules ko yarwa syringes.

Low kwayoyin nauyi heparins ba samar a cikin alluna.

Intramuscularly magani da ba a amfani.

Description "Gemapaksan" miyagun ƙwayoyi

Yana nufin kwayoyi tare da kai tsaye anticoagulant effects. The aiki sashi ne a cikin nau'i na enoxaparin sodium gishiri, wanda aka dauke a wanda aka samu daga heparin. Wannan canji na samar da wani babban adsorption lokacin gudanar subcutaneously da mutum low ji na ƙwarai.

An samar da Italian kamfanin "Italfarmako Spa" kamar yadda wani sarari, colorless ko haske-yellow bayani ga allura kunsasshen a syringes na 0.2, 0.4 ko 0.6 ml.

enoxaparin sodium sashi ne zuwa 2000 Iu zuwa 20 MG. 4000 Iu zuwa 40 MG da kuma 6000 MG na 60 Iu. The aiki sashi ne narkewa a cikin ruwa da alura.
Enoxaparin sodium bayyana a cikin wani sashi na 100 Iu da 1 MG na high hana ruwa guda sakamako a kan jini coagulation factor Xa da low tasiri antithrombin a kashi 28 iu da 1 MG.

A amfani da warkewa miyagun ƙwayoyi yawa a cikin cututtuka daban-daban ba ya haifar da wani karuwa a tsawon lokaci na jini hasãra.

Prophylactic sodium enoksaparinovaya sashi ba mai sãkẽwa ba da kunna m thromboplastin lokaci, ba ya karya wani platelet clumping da su dangane aiwatar da fibrinogen kwayoyin.

Low kwayoyin nauyi heparins a mafi miyagun ƙwayoyi maida hankali (6000 Iu a 0.6 ml) ana amfani da:

• domin far na thrombosis a cikin jijiyoyinmu daga cikin zurfi.
• samar da m angina da kuma tsokar mai ban mamaki infarcted tsoka yanayin a hade tare da acetylsalicylic acid.
• don rigakafin coagulation ƙãra ga tsawon lokaci da hemodialysis hanya.

Gabatarwa bayani subcutaneous kashi na 2000 Iu, kuma 4000 a 0.2 da kuma 0.4 ml, bi da bi, da ake amfani da su hana thrombosis da venous thromboembolic yanayin tsarin:

• a lokacin orthopedic m ayyukan hali.
• gado ga marasa lafiya da na kullum numfashi insufficiency ko cardiac tsarin naúrar 3 da kuma irin 4;
• m dauke da kwayar cutar ko rheumatic cututtuka, inda akwai hadarin factor ga jini clots.
• tsofaffi da marasa lafiya.
• tare da wuce haddi mai shaida.
• lokacin da hormone far.

Da miyagun ƙwayoyi da ake amfani da subcutaneously a cikin ciki bango, a cikin na baya da kuma anterolateral zone.

Magani ne contraindicated ga thrombocytopenia, zubar da jini, clotting cuta, ulcerative cuta daga cikin mucous membrane na ciki da kuma duodenum, subacute kwayan endocarditis, da ciwon sukari, ciwon sukari, high ji na ƙwarai da ciki.

"Gemapaksan" Medicine: farashin

A kudin allura dauke 2000 Iu sirinji a cikin 0.2 ml na shida guda na 955 rubles.

Don ƙarin sashi miyagun ƙwayoyi "Gemapaksan 'price jeri daga 1,500 rubles da fakitin da shida syringes.

Description "Clexane" miyagun ƙwayoyi

Yana nufin da wannan hanyar a kan tushen da enoxaparin sodium. Samar da Faransa kamfanin "Sanofi Aventis" kamar yadda wani injectable bayyananne bayani wanda zai iya zama colorless ko da dan kadan rawaya tint.

Akwai sashi "Clexane" shiri na 10000, 8000, 6000, 4000 da kuma 2000 iu na enoxaparin sodium zuwa 1.0. 0.8. 0.6. 0.4. 0.2 ml na ruwa miyagun ƙwayoyi, bi da bi. The aiki sashi a cikin bayani ne 1 MG 1,000 Iu.

Low kwayoyin nauyi heparins suna kerarre a gilashin syringes, wanda zai iya zama a cikin wani gungu 2 ko 10 guda.

Drug "Clexane" a kan rigakafin cutar ta HIV thrombotic da thromboembolic cuta a cikin jijiyoyinmu a lokacin da wani m baki alaka orthopedics, kuma hemodialysis.

A bayani da aka gudanar subcutaneously a kawar da venous thrombotic jihohin a cikin zurfin huhu da kuma a cikin jijiya.

Drug bi angina m yanayi na tsokar mai ban mamaki da kuma tsokar tsoka a tare da Allunan "asfirin".

"Clexane" Medicine: farashin

A kudin allura dauke 2000 Iu 0.2 ml da sirinji ne 175 rubles.

Daya naúrar kashi na 4,000 Iu da 0.4 ml na Rub 280 zai biya domin 6,000 Iu da 0.6 ml - 440 rubles 8000 Iu da 0.8 ml - 495 rubles.

A shirye-shiryen "Clexane" farashin da naúrar na 10 guda tare da kashi na 20 MG, 40 MG da 80 MG ne 1685, 2750, 4000 rubles.

Description "Fragmin" miyagun ƙwayoyi

The aiki bangaren da miyagun ƙwayoyi ne a wanda aka samu daga heparin abu wakilta dalteparin sodium. An samu ta hanyar depolymerization da mataki na nitrous acid , bi da tsarkakewa ta amfani da ion musayar chromatography. Dalteparinovaya sodium gishiri qunshi polysaccharide sarƙoƙi hõre sulphation, da wani talakawan kwayoyin nauyi na biyar dubu daltons.

Sababbin shiga protrude ruwa allura da kuma sodium chloride gishiri. Belgium medicament "Fragmin" manual ya bayyana a matsayin wani bayani ga allura subcutaneous da kuma igiyar jini gwamnati a cikin ruwa nau'i m colorless ko yellowish tint.

Its saki a monodose gilashin syringes na 2500 Iu da 0.2 ml. 5000 Iu da 0.2 ml. 7500 Iu da 0.3 ml. 10,000 Iu a 1.0 ml. 12,500 Iu a cikin 0.5 ml. 15,000 Iu da 0.6 ml. 18,000 Iu da 0,72 ml.

Drug "Fragmin" manual bada shawarar yin amfani da wani m gwargwado ga iko da jini clotting inji a hemodialysis da haemofiltration ayyuka da nufin lura da koda gazawar, to hana samuwar clots a tiyata.

A medicament aka gudanar ya kawar da thromboembolic raunuka bedridden marasa lafiya.

Magani bi angina, m kuma infarct tsokar mai ban mamaki jihar na tsokoki, symptomatic venous thromboembolism.

Description da miyagun ƙwayoyi "Anfibra"

Its low kwayoyin nauyi heparins ake da Rasha kamfanin OJSC "Veropharm". Akwai bayyana mafita ga allura, wanda zai iya zama colorless ko yellowish tint.

Muhimmi nufin ne enoxaparin sodium gishiri, wanda za a iya dauke 2000 Iu a 0.2 ml. 4000 Iu da 0.4 ml. 6000 Iu da 0.6 ml. 8000 Iu da 0.8 ml. 10,000 Iu a 1.0 ml. A distilled ruwa da ake amfani da sauran ƙarfi.

Yana prepacked a ampules ko syringes na 1ml, wanda suke 2, 5, da kuma 10 guda suna cushe a fakitoci na kwali.

Drug "Anfibra" wa'azi bada shawarar ga rigakafin thromboembolic al'amarinku, a lõkacin da aiki magudi da kuma hemodialysis da magani daga gudan jini samuwar a cikin zurfin-kwance tasoshin.

Magani zalunta da m yanayin angina kuma cardiac tsoka infarct jihar da ba hakori Q a kan electrocardiogram.

Description of "Fraksiparin"

By low kwayoyin nauyi heparins ne nadroparin alli, wanda aka samu a lokacin da depolymerization tsari. Its kwayoyin ne glycosaminoglycans, da talakawan kwayoyin nauyi daga abin da yake daidai 4.300 Daltons.

Shiri "Fraksiparin" (subcutaneous injections) a cikin abun da ke ciki ƙunshi alli hydroxide da gishiri nadroparin, wanda ake narkar da a injectable ruwa.

Sashi na aiki sashi ne 2850 ME a 0.3 ml. 3800 ME 0.4 ml. 5700 ME 0.6 ml, 0.8 ME 7600 ml, 9500 ME a 1 ml.

A shirye-shiryen ne a m, ko da dan kadan opalescent ruwa, wanda yana da wani haske rawaya launi ko gaba daya colorless.

Nadroparinovaya gishiri mai kyau gina jiki ta ɗaure zuwa antithrombin III, wanda ya haddasa kara hanawa na factor Xa. The abu activates hanawa samar da canji na nama factor, lowers jini danko da kuma ya karu platelet membrane permeability da granulocytic Kwayoyin. Saboda haka shi za'ayi antithrombotic sakamako daga cikin miyagun ƙwayoyi.

Injections "Fraksiparin" wajabta su hana thromboembolic al'amarinku, a lõkacin da aiki orthopedic magudi hali da hemodialysis. Da miyagun ƙwayoyi ne gudanar ga marasa lafiya da ciwon babban hadarin da jini gudan jini samuwar, m na numfashi insufficiency da kuma cututtukan zuciya, m angina pectoris, tsokar mai ban mamaki na tsokar tsoka to rasa Q-kalaman.

A amfani da anticoagulants a yaro-hali

Low kwayoyin nauyi heparins a ciki an sanya marasa lafiya da suke da zub da jini cuta to ba kafa placental jini clots da kai ga zubar da ciki, to preeklampsicheskomu na hawan jini, kwasfa da yaro kujeru da nauyi na jini, jinkiri da girma da tayi a cikin mahaifa, haddasa low baby nauyi.

Irin wannan anticoagulants aka wajabta mata a matsayin da zai yiwu hadarin gudan jini samuwar a cikin zurfin veins, misali ƙananan extremities, kazalika da huhu jijiya occlusion.

LMWH far akwai wata azaba mai tsari, a cikin abin da a ciki haƙuri shiga kullum miyagun ƙwayoyi karkashin fata a ciki.

Duk da haka, a lokacin da na asibiti yi da ka aka samu gwajin sakamakon wanda ta tabbatar da cewa yin amfani da irin wannan anticoagulants ne sau da yawa ba moriya ga kyau sakamako. Har ila yau, ya gano cewa low kwayoyin nauyi heparins far iya cutar da uwa tasa ta jiki hade tare da karin zub da jini da kuma rage zafi taimako a cikin aiki.

Wadannan karatu sun nuna cewa yarjejeniyoyin da anticoagulant magani iya ajiye mata da yawa daga ba dole ba zafi bayyanar cututtuka yayin ɗauke da jariri.

Umarnin kan yin amfani da shirye-shirye dangane da low kwayoyin nauyi heparin far an contraindicated a ciki.