Antibodies zuwa AT TPO

Har zuwa yau, a ko'ina cikin duniya, matsala na pathology na thyroid gland shine ba ya rasa ta dacewa. Rashin aidin a cikin jiki ne lura a 40% na manya da yara 50%. Wannan ya faru ne ba kawai ga batun haɓaka ba, amma har ma tasirin mummunar yanayi. A wannan yanayin, ana nufin Idinin inorganic don kira na hormones kamar T3 da T4, wanda adadin hormone mai maganin thyroid-stimulating (TSH) wanda ke sarrafa aikin glandar thyroid gwargwado ya dogara.

Ya kamata a faɗi cewa idan glandar thyroid ba ya aiki da ayyukansa a cikin isasshen tsari, wasu cututtuka (autoimmune) suna ci gaba a jiki. Ta haka ne, ganowar kwayoyin cutar AT TPO a binciken kwayoyin cutar zai iya nuna mummunar yanayin rigakafi dangane da dukan kwayoyin halitta. Wannan shi ne dalilin da ya sa daban-daban iri thyroid cututtuka da ake sa wa cikin nazarin da jini TSH matakin da kuma gaban antibodies ga AT TPO. Idan har yanzu ana lura da su, to, suna magana ne game da ilimin lissafi.

AT TPO wani enzyme ne wanda ke shiga cikin kira na hormones SHCHZ da kuma aiwatar da iodination na hormones. Yana da wani ɓangare na thyroid antigen.

Dalilin bincike zai iya zama alamar asali na cututtuka irin su goiter, hypo da hyperthyroidism, cutar cututtuka, thyroiditis, edema na shins. Bugu da ƙari, an tsara nazarin a lokacin daukar ciki don ƙayyade hadarin bunkasa thyroiditis bayan haihuwa (10% na mata suna da wannan cuta).

Ya kamata a lura cewa AT TPO, wanda ya saba da ita a cikin wani yaro yana da 5.6 U / ml, yana samar da aikin yin amfani da iodine cikin jiki. Magunguna zuwa wannan enzyme sun hana aikinsa, saboda haka an rage raunin hormones T4 da T3. Amma ba a dukkan lokuta, thyroid peroxidase nuna gaban wani autoimmune tsari.

Wannan bincike ne wanda ba makawa a cikin ganewar asali na thyroid cuta. Sakamakon tashin hankali a cikin aikinta ita ce alama ta farko na cigaban hypothyroidism. Idan ana amfani da hanyoyi masu mahimmanci na TPO, wannan cuta ta samu a cikin 94% na marasa lafiya, cutar cututtuka - a cikin kashi 84%, marasa cututtukan cututtuka marasa cututtuka - a cikin 15% na mutane. An samo wani ƙananan enzyme a cikin mutane masu lafiya, don haka batun baiwar da ke tattare da cututtukan cututtukan daban-daban a wannan yanayin ba a ishe shi ba.

Ya kamata a lura cewa a cikin yanayin idan AT TPO tayi girma, wannan yana nuna tsari kamar hypothyroidism. Wannan irin wannan cuta ya faru ne sakamakon sakamako na antibody da rage jinkirin aikin TPO, yin amfani da sinadarin oxidation na iodine, kuma, sabili da haka, karɓar nauyin aiki. A wannan yanayin, ba a haɗu da haukaran thyroid ba.

Nazarin yana ta hanyoyi da yawa. Mutum yana ɗaukar jini, wanda ya ƙayyade matakin TTG da T4. A cikin hali na al'ada T4 yi da kuma low TSH, da za'ayi a nazarin T3. A wannan batu, cikakken jarrabawar maganin rigakafi zuwa ATP ya zama dole.

Saboda haka, alamun binciken na binciken zai iya haɗa da tunanin goiter, hypothyroidism da AIT. Amma ya kamata a tuna da cewa babu kwayoyin cuta zuwa thyroid peroxidase ba ya ware yiwuwar kasancewar AIT a jiki. Sakamakon wannan enzyme a cikin jini ba ya bada amincewar mutum ɗari bisa kasancewar cutar ta asibiti, tun da yake a mafi yawan lokuta ATP TPO yana cikin mutane masu lafiya.

Daga wannan duka ya biyo bayan cewa an gano wannan enzyme, dole ne a gudanar da bincike mai zurfi tare da manufar kawar da hadarin AIT.

Saboda haka, ba tare da halin da ake ciki ba, thyroid peroxidase wani jarrabawa ne mai matukar muhimmanci game da rashin ciwon haɗari a cikin glandon thyroid, saboda haka ana amfani da irin wadannan nazarin a kusan dukkanin likitoci.