"Pyrazinamide" Allunan da bactericidal ko bacteriostatic sakamako na anti dangane da natsuwa. miyagun ƙwayoyi aiki ne kiyaye kawai a karkashin acidic yanayi (a PH na 5.6, kuma a kasa). a kan gona da magani yiwu ci gaba da juriya, wanda rage-rage da alama na amfani da magani da sauran antitubercular jamiái. Shiri "Pyrazinamide" (umurci manual ya tabbatar da wannan) shi ne mafi tasiri a lokacin da hallakaswa da tarin fuka kamar yadda ya gano a karon farko, tafiyar matakai caseous-pneumonic irin tuberkulomah, caseous lymphadenitis. Da miyagun ƙwayoyi lowers sufuri halin kaka urate da uric acid, hyperglycemia zai iya sa. Da miyagun ƙwayoyi daga cikin gastrointestinal fili kusan gaba daya da kuma da sauri tunawa. Jini sunadaran daura medicament 10-20%. Bayan awa daya ko biyu akwai matsakaicin maida hankali kudi. Magani ne da rarraba kan jiki ruwaye da kyallen takarda, za a ajiye a cikin gabobin, ciki har da huhu, hanta, koda da kuma sassa na encapsulated tuberculous raunuka. Yana nufin wuce da BBB. Metabolism auku a cikin hanta.
shaidar
Medicament "pyrazinamide" (martani masana tabbatar da shi) shi ne na farko zabi a lura da tarin fuka.
dosing regimen
An gano cewa monotherapy ba tasiri isa. A dangane da wannan miyagun ƙwayoyi "pyrazinamide" umurci manual bada shawarar yin amfani a hade tare da sauran magunguna da aiki tarin fuka. Domin manya, da sashi ne 30-35 MG / kg sau daya a rana. Ga marasa lafiya da yin la'akari kasa da hamsin kilo, da sashi ne uku Allunan (1.5 g). Lokacin da taro ne fiye da 50 kg kamata dauki 4 Allunan. (2 g). Ga yara matsakaicin kashi - 2 grams. Da miyagun ƙwayoyi ne riƙi da abinci. An shawarar zuwa sha wani magani a lokacin karin kumallo.
"Pyrazinamide" wajen. Umarnin don amfani. tsõratar
Magani yawan abin sama a yarda da likita ya umarta ba sa. Lokacin da ka karɓi wani babban adadin da miyagun ƙwayoyi lura illar na tsakiya m tsarin - dizziness, ciwon kai da sauransu. bayanin kula cuta a cikin hanta, m dyspepsia. Idan guba nuna symptomatic magani. Kafin da kuma a lokacin da tarin fuka magani a marasa lafiya fiye da shekara 60 ne da za'ayi kowane wata saka idanu na Manuniya na bilirubin, AST, uric acid da kuma Alt. A cuta na hanta bukatar kau da miyagun ƙwayoyi. A marasa lafiya da ciwon sukari mafi kusantar wajen samar da qarancin ruwa da. Lokacin da hade da magani shan magani "Rifampicin" za a iya lura hepatotoxicity. Lokacin hadedde tare da aikace-aikace shiri "Probenecid" yiwuwa rage tukar tumbi da a sakamakon, ta ƙara yawan guba. Akwai iya zama giciye-ji na ƙwarai da magani "INH", "Ethionamide" nicotinic acid da wasu wajen ciwon kama sinadaran tsarin. "Pyrazinamide" magani (umarnin don amfani da tabbatar da wannan) dace domin shekaru biyar. A abun da ke ciki da aka adana a cikin shãfe haske marufi, a yankunan kare daga haske.