Mene ne halayyar Fanconi ta ciwo? Haddasawa, Alamun, ganewar asali

Wannan ciwo da aka farko aka bayyana ta a Swiss pediatrician Toni Debre Fanconi, wanda kamu da cutar a wani yaro a shekarar 1931. A wannan likita ta cutar da aka bayyana ta bit, hankali m wasu cututtuka da kuma ciwo abubuwa, da babba da abin da ya kamata a yi la'akari glycosuria (glucose a gaban fitsari) da kuma albuminuria (bayyanar gina jiki a cikin fitsari).

A Sanadin Fanconi ciwo

Mafi sau da yawa wannan cuta ne na biyu, ci gaba tare da sauran magunguna. Wani lokaci ta faru da cewa Fanconi ciwo ne babban cuta a cikin wannan harka da shi za a iya samu kuma gaji. A dalilan iya zama:

• inborn kurakurai na metabolism.
• dalma da nauyi karafa ko guba abubuwa (Mercury, gubar, jinkiri tetracycline).
• bayyanar marurai malignancies (daban-daban na ciwon daji).
• wani rashi na bitamin D.

Wani lokaci kamar ciwo zai iya faruwa a matsayin mai wahala bayan konewa ko wasu na koda cututtuka. Fanconi ciwo a mata iya lalacewa ta hanyar hormonal imbalances cewa tashi bayan haihuwa.

Babban bayyanar cututtuka

Alamun da ciwo bambanta dangane da shekaru na haƙuri. Domin manya da farko alamun cutar raunuka ne: wuce kima urination, tsoka rauni da zafi a cikin kasusuwa da kuma gidajen abinci. Wannan sakamako ne ya bayyana da cewa cutar ne mutum m karancin gina jiki (sodium, potassium, alli).

Fanconi ciwo ne musamman kawo hadari ga yara, saboda shi zai iya sa babu ja da lalacewar da tsarin da matasa kwayoyin. Sau da yawa a cikin matasa marasa lafiya da ci gaban rickets, stunting kuma underdeveloped tsokoki, da wanda yake shi ne sakamakon wani rashin muhimmanci ma'adanai. A hadaddun cuta iya rage matakin da wata barã'aa cikin yaro, yin shi mafi saukin kamuwa zuwa cututtuka.

Duk da haka, da likita yi ya hada da lokuta inda marasa lafiya na shekaru daban-daban, akwai wani asibiti ãyõyin Fanconi ciwo. A wannan yanayin, wasu karshe za a iya sanya kawai da sakamakon jini da fitsari gwaje-gwaje.

Hanyoyin da ganewar asali

Tabbatar da gaban da ciwo a wani haƙuri samu tare da taimakon musamman dakin gwaje-gwaje da bincike da taya (fitsari da kuma jini), kazalika da da taimakon X-ray jarrabawa na ƙasũsuwa da gidajen abinci. Mafi sau da yawa, nazarin map nuna gaban wasu pathologies a Biochemistry. Domin Fanconi ta ciwo ne halin da:

• rage matakin na alli da phosphorus a cikin jini.
• take hakkin kai tsarin a koda tubules (wadda take kaiwa zuwa asarar alanine, glycine da proline).
• rayuwa acidosis (karu a jini bicarbonate maida hankali).

Fanconi ciwo za a iya bincikar lafiya tare da taimakon musamman na'urorin, kamar X-haskoki. A wannan yanayin diddigin cuta da kashi nakasawa da extremities matsayin dukan. Duk da haka, ba dukan marasa lafiya da irin wannan bayyanar cututtuka, haka dakin gwaje-gwaje gwaje-gwaje kamata a yi la'akari mafi m Hanyar ganowa cutar.

Hanyoyin da magani daga cuta

Saboda cutar Yanã da manyan lalacewar da acid-tushe da kuma electrolyte balance a cikin jiki, da magani dabarun da ya kamata a da nufin gyara wadannan Manuniya. Marasa lafiya suna karfafa sha yalwa na taya, musamman abun da ake ci, wanda ba ka damar mayar da matakin da m gina jiki (alli da phosphorus) da kuma bitamin D.

Kamar haka wajibi ne a rarrabe tsakanin likita da kuma wadanda ba pharmacological magani daga Fanconi ciwo. A farko irin ta dogara ne a kan yin amfani da shirye-shirye dauke da bitamin d3. A amfani da wannan kungiya take kaiwa zuwa wani karuwa a cikin abun ciki na phosphorus da alli a cikin jini. Lokacin da wadannan Manuniya isa al'ada matakan, bitamin ya kamata a katse.

Drug-free magani dogara ne a kan rage cin abinci far, wanda aka rage wa iyakance amfani da gishiri da kuma abinci da sa asarar sulfur amino acid. Lokacin da take hakki na PH-balance (acidosis), irin matakan ba zai isa, don haka marasa lafiya wajabta ƙarin magani darussa.

Hasashen da kuma rigakafin cututtuka

Forecast Fanconi ciwo ne da dangantaka da abin da ya faru na rikitarwa alaka koda aiki. Wannan yana bayyana a cikin nau'i na keta koda parenchyma (musamman tsoka da ke kewaye da jiki). Wadannan canje-canje na iya haifar da bayyanar pyelonephritis da na koda gazawar.

M hanyoyin cikin wannan hali ne kama da hanyar da ba-miyagun ƙwayoyi jiyya: da mãsu haƙuri dole ne a kullum kiyaye a cikin abinci da abun ciki na wani gina jiki da kuma ma'adanai.

A gaban wannan cuta a cikin zumunta da 'yan uwa na iya nuna ta watsa wa ƙaramin tsara, saboda Fanconi ciwo - shi ne mai hereditary cuta. Idan irin wannan links, lalle ne dole su gudanar a cikin zurfin nazari na jini da kuma fitsari a yara.

Fanconi ciwo a karnuka

Tun da wannan cuta ba sakamakon da tasiri na ɓangare na uku micro-kwayoyin da ƙwayoyin cuta, to kama su a kan kafofin watsa labarai ne ba zai yiwu. A ciwo ne iya zama sakamakon pathological wani rauni da kodan a cikin wasu mutane. Da dabbobi, da shi ne ya kamata a lura, a kalla a cikin karnuka kamu da wannan cuta, kuma.

A wanzuwar irin wannan ciwo a karnuka aka gane daga baya fiye da m adam cututtuka. Duk da haka, su ne quite kama a cikin halaye.

Ba duk breeds na karnuka shafi wannan cuta. Ta aka gani a beagles, whippets da kuma Norwegian Elk karnuka. Mafi sau da yawa bincikar lafiya da dabbobi a basenji Fanconi ciwo, daya daga cikin tsofaffin breeds na karnuka.

A tasiri na ciwo a kan kare ta jiki

Kamar yadda shi ne yanayin da mutumin, cutar ta sãme dabba ta kodan. Ya sha wuya da matakin na gina jiki a cikin jini, kuma a cikin fitsari bayyana m zuwa matsakaici mahadi da kuma ma'adanai. karnuka jiki fara kacokan amino acid da kuma bitamin, tare da tumbi, sakamakon cuta na tsokoki da kuma gabobin.

Tsawo daukan hotuna da cutar zai iya kai wa ga abke nauyi asara, dehydration na dabba, har ma da mutuwa. karnuka tsokoki hankali fara atrophy saboda rashin da ake bukata yawan abubuwa a cikin jini, don haka da haƙuri dabba ne ba aiki.

Alamun cutar ciwo a karnuka

Babban bayyanar cututtuka da cutar kamata a yi la'akari da} arfin ruwa ci, da kuma yadda copious. Animal jiki yayi kokarin mayar da ruwa balance, wadda take kaiwa zuwa wani m m musayar m.

A lokacin da kare ya fara rasa nauyi, ko da m da kuma yawan samar. Akwai gashi hasara, makamashi hasara, da kuma motsi. Marasa lafiya dabbobi iya jin zafi a cikin gidajen abinci da kuma kasusuwa. Abin lura shi ne cewa cutar sau da yawa bayyana kanta ba a farkon matakai na wani kare ta rayuwa (kamar yadda tsayayya wa wani mutum), amma wani wuri a tsakiyar, ƙarshen rayuwa sake zagayowar (tsakanin 5th da kuma 7th shekara). Domin basenji wannan shekaru ne musamman m, saboda fiye da 50% na karnuka fara zuwa sha mai kama da rashin lafiya a lokacin da aka ba lokacin. Saboda haka, masu wannan irin kamata ya mai da hankali domin hango ko hasashen bayyanar da ciwo.

Test alama ga karnuka ciwo

Wannan bincike da aka ci gaba da masana kimiyya a watan Yuli 2007. Yana ba ka damar gano gene alhakin da ya faru na Fanconi ciwo a karnuka. A wannan gwajin dabba iya zama gaba daya free daga yiwuwar samun cuta na iya zama wata cuta ko ainihin m da za a gitta su a kanta.

Mai kennels wanda asali karnuka, da a cikin su arsenal irin kwarewar da damar saye su dõgara a kan saye da lafiya kwikwiyo. Yana da ban sha'awa cewa internet ƙunshi dukan database, wanda wakilci rajista kwiyakwiyi na daban-daban Nurseries da sakamakon gwajin a kowane hali.

A developers na dakin gwaje-gwaje bincike ya nuna cewa gwajin ne ba wani unambiguous nuni da kwikwiyo ta daukan hotuna zuwa cuta. Duk da haka, kashi 90% na samu sakamakon gaskiya ne.

A eponymous ciwo Wissler-Fanconi

Wissler-Fanconi ciwo a yara akwai wata cuta da cewa yana da wani dangane da rashin lafiya, aka tattauna a wannan labarin. Wannan Pathology za a iya lura a wani yaro dake da shekaru uku zuwa shekaru bakwai, ko da yake akwai rubuce lokuta na ciwo, da kuma a wani a baya shekaru (kusan a cikin makon farko na rayuwa).

Wannan ciwo da aka yi fama da likitoci Wiesler da Fanconi a daban-daban sau da a sassa daban daban na duniya, wanda shi ne dalilin da ya sa shi ne ake kira, ya ƙunshi sunayen da likitoci biyu, ba Wissler ta ciwo ko Fanconi ciwo. Hotuna posted a wannan labarin daidai nuna bayyanar cututtuka da cutar, wato rashin lafiyan halayen. Bugu da kari, wani yaro haƙuri zazzabi iya ƙara, da kuma gidajen abinci sau da yawa fara su ji masa rauni da kuma kumbura. Complex magani shafi yin amfani da maganin rigakafi da kuma salicylates.