Anticoagulants - kwayoyi da shafi jini clotting

Karkashin al'ada yanayi, jini ne da wani ruwa wanda ya samar da da motsi ta jijiyoyi. A cututtuka da kuma parasitic cututtuka, kazalika da intoxications canza ta physico-sinadaran Properties, wanda adversely rinjayar da tafiyar matakai na rayuwa da kuma aiki na kayan ciki. Kamar wancan akanta yana clotting kudi. Yana za a iya kara da kuma jinkirta. A magani, yin amfani da wani yawa na pharmacological jamiái da taimakon wanda ba za ka iya daidaita gudun jini clotting. Anticoagulants - kwayoyi da rage gudu da aiwatar da coagulation na jini, kamar yadda wani wajen hanzarta wannan m mayar da martani, ya kira coagulants.

Ginshikai na coagulation da thrombus samuwar - wani hadadden biochemical aiwatar da kare jiki daga jini asara a lokacin jijiyoyin bugun gini mutunci take hakkin. Wannan tsari ne da za'ayi a kudi na prothrombin, wanda aka hada a cikin hanta, da kuma platelets, wanda bi da collagen zaruruwa na gefuna da lalace jirgin ruwa. A hydrolysis aiwatar kasaftawa platelet-arziki mahadi (adenozintrifosfatnaya da adenozindifosfatnaya acid), thromboplastin da vasoconstrictors - norepinephrine, epinephrine, serotonin. Su kunkuntar da jirgin ruwa lumen. Thromboplastin a ƙarƙashin rinjayar na alli da jini sunadaran da alaka da prothrombin da thrombin siffofin, wanda shi ne mai gina jiki (fibrinogen) yana tuba zuwa insoluble fibrin, sealing a jijiyoyin bugun gini lumen.

Jini clotting slows cututtuka hade tare da rage alli matakai a cikin jini, da rage a platelet ƙidaya, prothrombin kira rashin lafiya na fibrinogen, thrombokinase kasa aiki da kuma bitamin K. The coagulants amfani da magani, thrombin, fibrinogen, alli chloride, menadione, aminocaproic acid, kayan lambu shirye-shirye (nettle ganye, ruwa barkono).

Anticoagulants - kwayoyi da hana da nazarin halittu aiki da tsarin, wanda ya samar da jini coagulation, da hana samuwar clots a jini. Sun hana duk ko wasu daga cikin bulan na jini clotting. An sani cewa jini ruwa jihar yana kiyaye ta musamman enzymes da antitrobminom. Domin hana samuwar jini clots, anticoagulants amfani kai tsaye mataki. Su shafi cikin jini clotting dalilai jinkirta aiwatar a cikin jiki ne, ko tube. Sodium citrate (sodium citrate) da kuma EDTA (ethylenediaminetetraacetate acid) kisa da ionized alli na jini da kuma maida shi cikin alli citrate ko dai complexed da EDTA. A dangane da kau da alli ions daga jini clotting tsarin da aka kafa thrombin da fibrin. Heparin inactivates thrombogenic dalilai da damuarn hira da prothrombin zuwa thrombin. Anticoagulants - kai tsaye mataki na kwayoyi wajabta transfussion da Hematology dakin gwaje-gwaje karatu don rigakafin jini clotting kuma domin lura da cututtuka da cewa suna tare da wani kara jini clotting. Wadannan kwayoyi suna amfani ga yin rigakafi da magani daga thromboembolic rikitarwa.

Anticoagulants na kai tsaye ba mataki - bishydroxycoumarin, coumarin, sinkumar - toshe kira na enzymes cewa suna da hannu a cikin jini clotting. Sun hana thrombin samuwar a cikin hanta. Wannan tsari tasowa a cikin kwayoyin a cikin 12-72 sa'o'i da aka nuna a wani lokaci na daga biyu zuwa kwanaki goma. Wannan shi ne wani dogon-aiki da magunguna. Anticoagulants - kwayoyi kaikaitaccen wajabta domin yin rigakafi da magani daga thrombosis, embolism, thrombophlebitis.