"Levodopa / benserazide-Teva": umarnin don amfani, analogs da kuma sake dubawa

Abin da zai iya maye gurbin wannan miyagun ƙwayoyi a matsayin "L-Dopa / benserazide"? Analogues wannan magani da za a tattauna daga baya a cikin labarin. Za mu kuma gabatar da pharmacological halaye na wannan kayan aiki, ta hanyar saki, alamomi da kuma hanyoyin da amfani.

Form, abun da ke ciki, marufi

A medicament "levodopa / benserazide-Teva", da wa'azi da aka kewaye a cikin wani kwali akwatin da aka dakatar a cikin nau'i na Allunan, kunsasshen a cikin kwalabe na 30, 20, 60 ko 50 na fadiwa. Babban abu na miyagun ƙwayoyi levodopa da benserazide protrude. Game da ƙarin aka gyara, da suka hada da: mannitol, alli hydrogen phosphate (anhydrous), MCC, crospovidone, pregelatinized masara sitaci, colloidal silicon dioxide, povidone K25, magnesium stearate, da kuma wani colorant ja ferric oxide.

pharmacological halaye

Shiri "levodopa / benserazide" wakiltar hada antiparkinsonian wakili wanda ya hada da a cikin abun da ke ciki da decarboxylase hanawa (gefe) aromatic L-amino acid da kuma dopamine precursor.

A parkinsonism, dopamine aka saki daga muhimmi ganglia a kasa yawa. Its maye ne da za'ayi ta hanyar karbar levodopa, wanda shi ne mai rayuwa precursor na dopamine.

The most ɓangare na wannan kashi a gefe kyallen takarda ne tuba zuwa cikin dopamine, wanda ba ya shiga a cikin antiparkinsonian sakamako, tun da shi ba ya shiga ta hanyar da jini-kwakwalwa shãmaki, kuma shi ne ma alhakin yawancin m halayen.

The motsi na miyagun ƙwayoyi

Kamar yadda masana faye hali da miyagun ƙwayoyi a tambaya, ko kuma wajen, ta sanadin motsi-tsari? Levodopa da benserazide tunawa yawanci a cikin kananan hanji. Lokacin da samun magani a cikin ganiya maida hankali ne kai bayan game da 65 minutes.

Ya kamata a lura da cewa, musamman sha na wadannan abubuwa dogara a kan intragastric PH Manuniya, kazalika da kudi na tukar tumbi da na ciki da abinda ke ciki.

Lokacin da samun levodopa nan da nan bayan da abinci ta yi cincirindo a jini ne game da 30% kasa, kuma da har na sha - 15% m.

A manyan yawa, wannan magani da aka samu a cikin kananan hanji, koda, da kuma hanta. Duk da haka, kawai 1% shiga cikin kwakwalwa.

rabin-rai da miyagun ƙwayoyi a karkashin review, lokaci ne sa'o'i uku.

Ba kamar levodopa, irin bangaren halitta kamar yadda benserazide, ba shiga cikin BBB. Wannan abu da aka tara a cikin huhu nama, koda, hanta da kuma kananan hanji.

Lokacin gudanar?

Drug "Levodopa / benserazide" ne anti-Parkinsonistic. Saboda haka, yana da bu mai kyau ya nada:

• parkinsonian ciwo (ciwo togiya ne ya sa ta antipsychotic kwayoyi).
• Parkinson ta cutar.
• m kafafu ciwo, ciki har da a mutane da kullum na koda gazawar da suka yi a kan dialysis.

Haramta yin amfani

Ko akwai contraindications a cikin miyagun ƙwayoyi "Levodopa / benserazide-Teva" (martani nuna su tushe, mu yi la'akari da ƙasa)? Wannan magani an haramta sanya:

• shafi tunanin mutum da rashin lafiya.
• hypersensitivity zuwa jamiái abubuwa.
• tsanani disturbances a cikin endocrine tsarin, kazalika da tasoshin da kuma zuciya.
• cututtuka na koda da hanta, amma ci gaba da m kafafu ciwo tare da hada amfanin ƙasa dialysis.
• lactation.
• ƙulli glaucoma.
• layi daya aikace-aikace nonselective Mao hanawa.
• ciki;
• kasa da shekaru 25 da shekaru.
• na haihuwa shekaru a cikin mafi kyau jima'i, ba ta amfani da m hanyoyin da maganin hana haihuwa.

"Levodopa / benserazide": cinikayya sunan, Hanyar da aikace-aikace

Sayi shawara medicament iya zama a wani kantin magani. Ciniki sunan da miyagun ƙwayoyi sauti kamar "Levodopa / benserazide-Teva".

A abin da sashi gudanar ga marasa lafiya dauke magani? Jiyya daga wadannan nufin fara tare da wani low kashi, wanda aka hankali ya karu (ga kowane haƙuri akayi daban-daban).

A cewar masana, ya kamata ka kauce wa high allurai na wannan magani. Wadannan dosing regimen kamata a yi la'akari a matsayin general shawarwarin.

"Levodopa / benserazide", dauka baki domin akalla rabin sa'a kafin ko bayan 65 minti bayan da wani abinci.

Mutane baya shan wannan na nufin, a farkon far bayar da shawarar yin amfani da 12.5 / 50 MG levodopa da benserazide hudu sau per day. Tare da kyau tolerability na da sashi ne ya karu da wannan adadin kowane kwanaki uku. M titration ne da za'ayi tare da wani mita na 1 kowane kwana 30.

Yawanci, da warkewa sakamako bayan gwamnati da miyagun ƙwayoyi lura riga lokacin samun 100 MG benserazide da 400 MG na levodopa kowace rana.

A mafi sashi daga cikin miyagun ƙwayoyi da rana ne 800/200 MG na levodopa da benserazide bi da bi. Ya ce adadin medicament ya kamata a raba ta 4 ko fiye allurai. Kamar haka suka kamata a rarraba yadda za a samar da haƙuri da mafi kyau duka warkewa sakamako.

Tare da ci gaban m halayen kamata kara da kashi ko dakatar, ko rage shi.

A sashi regimen da miyagun ƙwayoyi a musamman na asibiti yanayi

Ta yaya ya kamata in yi da magani "Levodopa / benserazide"? Guest masana bayar da rahoton cewa marasa lafiya da fuskantar tsanani mota hawa da sauka, da kullum kashi na wannan magani ya kamata a raba da fiye da 4 m.

A tsufa, kara da sashi ya kamata faru sannu a hankali.

The kwarewa da miyagun ƙwayoyi a yara da kuma matasa da aka iyakance.

A hanta da na koda gazawar medicament kashi gyara ake bukata.

Tare da ci gaba maras wata-wata ƙungiyoyi, musamman a cikin daga baya matakai na magani, shi ne shawarar rage sashi. Haka ya shafi cikin makaruhai sakamakon da CCC.

Bayyanar cututtuka na yawan abin sama

Yanayin aiki "Levodopa / benserazide" high allurai da miyagun ƙwayoyi, ma'ana, wanda za a gabatar a kasa, zai iya sa bayyanar cututtuka irin su tashin zuciya, sababbu, involuntary ƙungiyoyi na wani pathological yanayi, rashin barci, amai, da ruɗewa. Ya kamata kuma a lura da cewa, ci gaban irin wannan bayyanar cututtuka iya yi jinkiri saboda rage sha na da miyagun ƙwayoyi daga hanji.

Domin lura da yanayin yadda aka bayyana symptomatic far (wajabta antiarrhythmic kwayoyi, numfashi analeptic da neuroleptics), kuma a kai a kai saka idanu da muhimmanci ayyuka na jiki.

hulda

Drug "Levodopa / benserazide" interacts tare da sauran kwayoyi kamar haka:

• Karbar trihexyphenidyl rage kudi amma ba har na sha na levodopa.
• Antihypertensive kwayoyi, opioids, neuroleptics da kuma kayayyakin dauke da wani reserpine, hana mataki na bayyana medicament.
• Aikace-aikace tare da antacids rage nisan da sha na nufin karkashin shawara ta 32%.
• Metoclopramide qara sha kudi na levodopa.
• Kudin shiga pyridoxine rage sakamako na antiparkinsonian magani.
• Levodopa da benserazide iya ba za a yi amfani da tare da tare da wadanda ba zabe Mao hanawa.
• An fito da miyagun ƙwayoyi potentiates da mataki na sympathomimetic.
• Levodopa da benserazide tare da sauran antiparkinsonian kwayoyi kara habaka da kyawawa da makaruhai effects.

Specific bayanai

Kafin ka fara shan "Levodopa / benserazide" ya kamata sha cikakken kiwon lafiya jarrabawa. Wannan shi ne saboda gaskiyar cewa akwai da dama daga cututtuka a cikin abin da amfani da wannan kayan aiki ya zama tare da matsananci hankali:

• A gaban bude kwana glaucoma far ba a fara har sai da cikakken waraka daga mãsu haƙuri.
• Haramta miyagun ƙwayoyi abruptly soke "halothane", kamar yadda zai iya bayar da gudummawa ga ci gaban da neuroleptic m ciwo a lokacin janar maganin sa barci.

Ya kamata kuma a lura da cewa, a cikin farkon ya karɓarsu ga magani physiological sigogi iya canza ta da mãsu haƙuri. A wannan batun, a cikin shakka daga jiyya ake bukata don a gwada a kai a kai wajen saka idanu da dace aiki na duk kayan ciki.

Mutane da ciwon sukari ya zama sau da yawa a rana duba jini glucose.

A kudin da miyagun ƙwayoyi da kuma ta analogues / ma'ana

Nawa ne wannan miyagun ƙwayoyi a matsayin "L-Dopa / benserazide-Teva"? Farashin wannan magani ya dogara da yawan Allunan da fakitin. Yana kullum jeri 600-1250 rubles.

Abin da za a iya dauke su maye gurbin antiparkinsonian miyagun ƙwayoyi? Its main analogues da ma'ana hada da wadannan nufin: "Zimoks", "Duellin", "Isik," "Lac" "Dopar 275", "Carbidopa / Levodopa," "Sinemet", "Sindopa", "Tidomet", " Tremonorm ". Ya kamata a nan da nan ya lura da cewa pharmacological halaye da kuma hanyoyin yin amfani da wadannan kwayoyi na iya bambanta da yawa daga sama. Saboda haka, don maye gurbin su, "levodopa / benserazide-Teva" ya kamata kawai likita ta shawarwari.

Feedback a kan tasiri na da miyagun ƙwayoyi

Ba asiri da cewa Parkinson ya cutar ne mai matukar tsanani cuta. Bugu da kari, shi ne mai tsanani kalubale ga marasa lafiya da kuma 'yan uwa.

A cewar kwararru da kuma masu amfani da lokacin lura da wannan magani rinjayar duk marasa lafiya daban. Wani lokaci ko da a karkashin m dubawa na wani likita da wani dogon liyafar da Allunan lura a adam marasa lafiya irritability da bouts na fitina. Har ila yau, gefen halayen faruwa kamar yadda hallucinations da juwa.

By rage sashi a wasu marasa lafiya cututtuka da shafi tunanin mutum cuta suna bace, yayin da mota aiki ba sosai. Duk da haka, a wasu marasa lafiya, ko bayan cikakken an daina miyagun ƙwayoyi duk da shafi tunanin mutum cuta nace. Bugu da kari, su motor aiki tabarbarewa.Idan muhimmanci.

A dangane da duk sama, za mu iya lafiya kammala da cewa, a liyafar da kudi dole za a shirya domin ci gaban mai tsanani illa, kamar yadda aka ambata a sama.

Bisa ga rahoton na masana, da aiwatar da magani daga anti-Parkinsonistic shiri ya kamata faru ne kawai a karkashin tsauraran dubawa na likita. Wannan zai ba da damar ko waƙa da minti canje-canje a cikin haƙuri da yanayin da zuciya da jijiyoyin jini tsarin da psyche, kuma idan ya cancanta - to amsa a dace hanya.