Da miyagun ƙwayoyi "Kortef": umarnin don amfani, alamomi, contraindications, sashi, reviews

Glucocorticosteroids (GCS) an kira roba kwayoyi, wanda suke analogues na na ciki hormones samar da adrenal bawo. GCS yana a kan jikin mutum wani iri-iri effects: anti-mai kumburi da desensitizing, immunosuppressive, anti-mai guba da kuma antishock.

Yau Pharmaceutical kasuwar na Rasha shi ne mai fadi da jerin irin magunguna. Daya daga cikinsu shi ne "Kortef". Umarnin don amfani da shawarar shan shi da yawan cututtuka.

Tsari da kuma abun da ke ciki

A medicament ne aka yi nufi ga baka gwamnati. Babban aiki bangaren "Kortef" shiri (umarni dauke da wannan bayanai) ne hydrocortisone - a hormone samar da adrenal gland. Domin tsari da kuma gida amfani an yi amfani da likita muhallin halitta hydrocortisone ko ta esters.

A magunguna "Kortef" wannan hormone yana kunshe ne a cikin adadin 10 MG. Kamar yadda ƙarin protrude abubuwa irin alli stearate, masara sitaci, sucrose, lactose, ma'adinai da man fetur, da kuma sorbic acid.

Babban fom in wanda shi ne samarwa masu amfani da 'Kortef "- Allunan. Umarnin don amfani, real jinya da kuma marasa lafiya ce da high dace da miyagun ƙwayoyi. Allunan na madauwari siffar da wani layi a kan surface kuma embossed a kan shi labeled «CORTEF10» kunsasshen cikin vials duhunta gilashin (kowane cushe da 100 guda). Saya magani kawai a kan ganin likita.

pharmacodynamics

Kamar yadda aka ambata a baya, da miyagun ƙwayoyi yana da dogon jerin effects a kan jikin mutum: anti-mai kumburi da antishock, desensitizing kuma anti-rashin lafiyan, anti-mai guba, immunosuppressive da antimetabolite. Description da miyagun ƙwayoyi (umurci manual) ya ƙunshi bayani game da taro na matakai don wanda da miyagun ƙwayoyi shafar. Yana damuarn a saki mai kumburi shiga tsakani da kuma muhimmanci slows a saki cytokines (interferon, interleukins) daga macrophages da lymphocytes.

Har ila yau, "Kortef" stimulates glycogen ajiya a cikin hanta, qara adadin glucose dauke a cikin jini, da ruwa slows saukar da excreted Na + kuma K + ƙaruwa. Tare da kai tsaye hannu na medicament rage-rage samar da histamine (matsakanci, t. E. Sulfu ake bukata ga nan da nan da irin rashin lafiyan halayen).

Bugu da ƙari kuma, shirye-shiryen da Kortef "umarnin don amfani da ce wajen rage yawan salon salula infiltrates (cell abubuwa da jini da kuma Lymph) da kuma a cikin saran kumburi foci locomotor aiki na leukocytes da lymphocytes taimaka wajen rage da capillary permeability. Da miyagun ƙwayoyi damuarn da kira da kuma qara kudi na gina jiki rashin lafiya.

"Kortef" rinjayar da pituitary da kuma cike da samar da corticotropin (ACTH), ba tare da wanda ya iya gaba daya dakatar da aiki na adrenal bawo.

Medicine "Kortef": wa'azi, aikace-aikace

Guest masana sun ce kafin mu da magani da ake amfani a fannoni daban daban na magani. Ana amfani da a cire haƙuri daga mai guba, traumatic, konewa, cardiogenic, na sarrafawa buga a lokuta inda misali antishock far kawo wani sakamakon. Bari mu bincika wadannan maki a more daki-daki.

Saboda haka, yadda marasa lafiya wajabta Categories "Kortef"?

Umurnai na amfani, description magani ne ya kawo wa masu amfani da bayanai game da yiwuwar ta yin amfani a endocrinology. A nan, da miyagun ƙwayoyi zai zama tasiri ga cututtuka kamar insufficiency na adrenal bawo aiki, thyroiditis (subacute form), adrenal hyperplasia (m yanayi), hypercalcemia, abin da ya bayyana a kan bango na malignancies.

Bugu da ari, a Rheumatology "Kortef" lallai bayyana kanta a lura da bursitis, amosanin gabbai (gout, psoriatic rheumatoid), ankylosing spondylitis, nonspecific tenosynovitis. Good sakamakon da aka cimma, marasa lafiya shan "Kortef" a tsari lupus erythematosus, m rheumatic cututtukan zuciya, polymyositis, epicondylitis.

Akwai alamomi na amfani "Kortefa" da kuma a cikin filin na dermatology. Ga da miyagun ƙwayoyi ne tasiri da magani daga pemphigus, mycosis fungoides, herpetiformis, kuma exfoliative dermatitis. Har ila yau, an wajabta m psoriasis, seborrheic dermatitis, erythema multiforme nauyi kwarara.

Allergists rubũta "Kortef" da magani ciwo, rashin lafiyan rhinitis asali, tare da atypical da lamba dermatitis, Bronchial fuka da kuma mutum hypersensitivity zuwa kwayoyi.

Masana-ophthalmologists matsayin yi na nada "Kortefa" tare da yawan cututtuka. A medicament ne tasiri a corneal ulcers da conjunctivitis na rashin lafiyan asali, tare da keratitis da iritis, iridocyclitis lokacin, neuritis, uevite, da dai sauransu A fagen Oncology GCS "Kortef" wajabta a cutar sankarar bargo, a ilimin tsarin jijiyoyi - .. Mahara sclerosis.

Ina kuma yi amfani da "Kortef"? Umurnai na amfani ƙunshi bayanai dõmin ya designate ta marasa lafiya pulmonology (symptomatic sarcoidosis, fulminant na huhu da tarin fuka, tsammãni ciwon huhu) da kuma Hematology (secondary thrombocytopenia, aplastic anemia ko hemolytic, erythroblastopenia).

Aikace-aikace da kuma dosing

A medicament "Kortef" ne aka yi nufi ga baka gwamnati. Duk da haka, domin samar da lyophilizate na bayani "Solu-Kortef" umurci manual umurci gudanar intramuscularly, intravenously (bolus ko jiko) da kuma periarticular jakar.

Kamar yadda na baka gwamnati, da farko sashi iya bambanta daga 20 zuwa 240 MG a rana dangane da kamu da cutar da kuma mai tsanani daga cikin haƙuri da yanayin. A mafi kyau duka kashi a kowane hali da aka zaba ta hanyar rage farko soma da mafi karami cewa za ta samar da ake so sakamako.

A m yanayi da kuma bukatar gaggawa magani shawarar igiyar jini magani management "Solu-Kortef". Umurnai na amfani bayyana da wadannan misali makirci. Na farko da bayani na 100 MG (na farko kashi) anyishi a kan rabin minti daya. A na gaba girma daga cikin miyagun ƙwayoyi a 500 MG ya kamata a gudanar a cikin minti 10. Bugu da ari, kowane 2-6 hours, da hanyoyin da ya kamata a maimaita, ba tare da ya manta to ci gaba da saka idanu haƙuri da yanayin.

Dole ne mu tuna cewa a cikin high allurai, "Sol-Kortef" amfani kawai da lokacin da karfafawa na haƙuri, amma don ba fiye da 3 days.

V / m "Kortef" gudanar a wani juz'i na 125-250 MG / rana. M miyagun ƙwayoyi effects bayyana bayan 6-25 sa'o'i bayan hanya da za su iya wuce daga kwanaki da dama zuwa makonni da dama.

Idan dole, "Kortef" injections sun ciki-articular ko periarticular a cikin jakar. A tasiri sashi na manyan gidajen abinci (kafada, gwiwa, hip) ne 25-50 MG, amma ga m yanayi da kuma iya isa 100 MG. Domin karami gidajen abinci (magincirõri, wuyan hannaye, phalanges) zai zama isa allura girma na 10-20 MG, sanya 1 lokaci. Maimaita hanya shawarar kowane 1-3 makonni (wani lokacin ake bukata da kuma mafi sau da yawa - kowane 3-5 days).

A general, game da miyagun ƙwayoyi far "Kortef" Sashi da kuma gwamnati za su iya kawai zabi zalunta likita. Nan da dakatar da magani ne ba kyawawa, wani babban yiwuwar sake komowa. Gamawa magani faruwa da hankali rage sashi.

Contraindications ga yin amfani da "Kortefa"

Akwai jerin cututtuka da kuma yanayin da kwayoyin, idan ba a yarda ya dauki karkashin shawara ne magani. Wannan parasitic cututtuka na kwayar, fungal ko kwayan asalin (canjawa wuri a cikin 'yan baya, dake faruwa a lokacin).

Kada Ka sanya shi, idan haƙuri ne kamu da psychosis a cikin m mataki, decompensated ciwon sukari ko mutane sha hypothyroidism, hyperthyroidism, hauhawar jini, peptic miki gastrointestinal cututtuka da kuma dermatological raunuka, peptic miki ko da cututtuka yanayi.

Akwai jerin contraindications for intraarticular allura "Solu-Kortef" miyagun ƙwayoyi. Kada rubũta magani, da kuma a cikin wani yawan matsalolin da zuciya da jijiyoyin jini tsarin, ciki har da a kwanan nan tarihi na tsokar zuciya infarction.

Ga guda kashi, ko da ga "m" bukatar contraindication zuwa aikace-aikace ne mutum hypersensitivity da miyagun ƙwayoyi aka gyara.

a ke so effects

Daga dalilai da dama ya dogara a kan mita da kuma kwarjinin illa, a jerin wanda yana dauke da miyagun ƙwayoyi zuwa "Kortef" umurci manual. Alamomi, kashi, duration daga cikin shakka wajabta ta halartar likita dole a lura ba tare da kasa. Wasu muhimmancin ne ma a haɗe zuwa da kiyaye da circadian kari na makõma (hawa da sauka tsanani na daban-daban nazarin halittu tafiyar matakai hade da canji na dare da rana).

A tsarin endocrine a mayar da martani ga samun "Kortefa" shi ne iya amsa ga wani karu a ji na ƙwarai to glucose da kuma ci gaban ciwon sukari steroid yanayi, aiki na adrenal danniya. Akwai damar bunkasa Cushing ta ciwo, babban bayyanar cututtuka daga waxanda suke da jinjirin wata-dimbin yawa irin fuska, kiba, pituitary irin karuwa a kudaden da jini, myasthenia gravis, daban-daban cuta na hailar sake zagayowar a mata.

Reaction na gastrointestinal fili zai iya zama bayyanar cututtuka irin su tashin zuciya da kuma amai, pancreatitis, da kuma daban-daban steroid ulceration na narkewa kamar fili, zubar da jini, da kuma perforation ya (GI) ganuwar, erosive esophagitis.

Daga gefe na zuciya da jijiyoyin jini m halayen zuwa "Kortef" (mai amfani ya tabbatar da wannan bayanai) ne arrhythmia, bradycardia, thrombosis, karuwa a jini Manuniya. A kan backdrop na wani m da subacute nau'i na "Kortef" tsokar zuciya infarction iya haifar da yaduwar necrosis, hanawa da samuwar tabo nama, wanda zai iya haifar da katsewa na zuciya tsoka.

Kullum amsa barnatar da yin amfani da "Kortefa" ko ta wani hanya na iya zama wani iri-iri na gabobin da kuma tsarin na jikin mutum. Zai yiwu manifestations na tsakiya m tsarin da azanci shine gabobin, cuta da metabolism da musculoskeletal tsarin. Suna iya nuna wani iri-iri na rashin lafiyan halayen. A mafi cikakken bayani yana kunshe ne a cikin wani medicament don amfani "Kortef" umarnin.

Pregnancy kuma lactation

A cikin tsawon gestation da jariri nono tsananin haramta medicament "Kortef" umurci manual. Description (a gaban wasu siffofin magani benzyl barasa yayi magana don kansa), da miyagun ƙwayoyi yana dauke da bayanai game da yiwu effects na yin amfani da "Kortefa" a irin wannan lokaci kamar yadda gazawar na adrenal aiki, Jihar breathlessness, mutuwa.

Yara, iyaye mata wanda a lokacin daukar ciki da aka tilasta ya dauki hydrocortisone, ya zama karkashin kusa dubawa na likita ma'aikatan da wani ra'ayi zuwa farkon ganewa na ãyõyin adrenal insufficiency.

Abin da ya kamata ka kula da?

A lura da amfani da miyagun ƙwayoyi "Kortef" User Aikace-aikacen da shawarar a rage cin abinci iyakance gishiri ci. Bugu da kari, jiki dole ne sami isasshen furotin. Har ila yau a wannan lokaci shi ne unacceptable rike da wani irin alurar riga kafi. Wajibi ne a gudanar da gudana saka idanu na jini sigogi, da maida hankali glucose a cikin jini, kuma ta clotting. Yana da muhimmanci wajen saka idanu da fitsari fitarwa da kuma nauyi na haƙuri.

Idan wani stressful yanayi, mutane jurewa warkewa hanya tare da "Kortefa" bukatar kara da sashi na corticosteroids. Game da marasa lafiya fama da tarin fuka, da cewa su ne a cikin aiki mataki dole dauki "Kortef" kawai a layi daya da daidai far nufi ga lura da tamkar cuta. A da tarin fuka da ke faruwa a wani latent tsari, ko a aiwatar da lanƙwasa tuberculin gwaje likita ma'aikatan kamata a hankali saka idanu haƙuri da yanayin da kuma rubũta dace chemoprophylaxis idan ya cancanta.

Idan ganawa da miyagun ƙwayoyi jawo ci gaban da sakandare adrenal insufficiency, yana yiwuwa ya normalize da halin da ake ciki ta hanyar hankali rage kashi. Bayan far da aka kammala, har ma ga 'yan watanni za a iya gani da irin wannan gazawar. Stressful yanayi da cewa sun faru a cikin wannan lokaci ne mai nuni ga zaman majalisar na tashar GCS.

Amma ga sauki herpes cututtuka na ido, da "Kortef" (mai amfani, aikace-aikace, real masana suna dauke a cikin labarin), da kuma wani corticosteroids kamata a yi amfani da taka tsantsan, tun da shi ne zai yiwu ci gaban corneal perforation.

Ma'aikatan kiwon lafiya, ya kamata sane da cewa a lokacin da magani "Kortefom" wasu cututtuka na iya zama asymptomatic, a latent form, kuma suna da sãɓãwar launukansa digiri na tsanani. Tare da kara allurai na corticosteroids amfani qara da alama na tasowa latent cututtuka. E. A karkashin tasirin "Kortefa" snizhet juriya ga kamuwa da cuta, rage ikon localize tushen kamuwa da cuta.

Waɗanda aka sanya immunosuppressive allurai "Kortefa" ko wani corticosteroids suna shawarar ba zo a cikin lamba tare da mutanen da suke da karambau ko kyanda. Idan irin wannan lambobi bai dauki wuri, kana bukatar ka tuntube su zalunta likita nan da nan.

SCS iya zama wani dalili na hankali cuta, ko don inganta kyakkyawar psychotic bayyananen, ta ƙara wani tunanin rashin zaman lafiya.

Akwai bayanai da cewa a wasu marasa lafiya a kan bango na "Kortefa" (ko wasu corticosteroids) ɓullo da Kaposi ta sarcoma. Duk da haka, bayan da soke medicament lura asibiti gafarta musu.

Domin dalilin cewa rikitarwa bayan shan miyagun ƙwayoyi ne kai tsaye dogara a kan duration da kuma sashi kudi, da yanke shawarar fara lura shakka, ta duration da kuma canja dosages likita daukan lokacin da kimantawa da zargin da ake yi amfanin da ya yi haƙuri kuma m kasada da miyagun ƙwayoyi.

Hulda da sauran kwayoyi

Saboda haka, za mu tattauna abin da ya ƙunshi "Kortef". Umarnin don amfani, alamomi da contraindications da kuma gefen sakamakon da miyagun ƙwayoyi kuma dauke. Ya zauna a lura da cewa, wadanda gwani a cikin saduwa da miyagun ƙwayoyi a marasa lafiya kamata ka sani cewa hydrocortisone aka mayar da martani tare da wani iri-iri abubuwa, kuma wadannan mahadi na iya haifar da tsanani lalacewar jiki.

Da fari dai, hydrocortisone pharmaceutically m tare da sauran kwayoyi da kuma tare da wani dangane yunkurin iya samar da insolubles. Na biyu, shi qara yawan guba na cardiac glycosides, a sakamakon iya bunkasa hypokalemia, sa'an nan akwai wani hadarin karuwa da arrhythmia.

Tare da kai tsaye hallara "Kortefa" (musamman, ta kuriyar) qara kudi na tukar tumbi da acetylsalicylic acid (ASA) da abun ciki matakin a cikin jini tayi.

A amfani da hydrocortisone a kan bango na live cutar alluran iya fararwa da kunnawa da ƙwayoyin cuta da kuma ci gaban cututtuka.

Paracetamol a jummai da "Kortefom" na iya zama hepatotoxic. A dogon lokaci gwamnati qara taro na folic acid a cikin jiki. A high dosages hydrocortisone rage tasiri na somatropin (girma hormone).

Bugu da kari, babban aiki sashi rage tasiri na hypoglycemic magani amma qara anticoagulant sakamako na coumarin Kalam. "Kortef" cike da effects na bitamin D a kan sha aiwatar da Ca ₂ + a cikin hanji lumen. Ƙarƙashin rinjayar hydrocortisone qara yawan guba na cyclosporine da ketoconazole.

A gaban abubuwa irin ephedrine, theophylline, rifampicin, barbiturates wani warkewa sakamako na GCS sakamako tayi. Acne da kuma ci gaban hirsutism (wuce kima girma na m - m da duhu - gashi a mata namiji juna) ya biyo baya da liyafar tare da sauran hydrocortisone steroid hormonal kwayoyi (anabolic steroids, estrogens, na baka hana).

A ra'ayi na masu amfani da game da miyagun ƙwayoyi "Kortef"

"Kortef" ma rikitarwa miyagun ƙwayoyi zuwa da wani mummunan feedback. Ko da yake tabbatacce yawa sau more. Description magunguna "Kortef" (reviews na ma'aikatan kiwon lafiya sun tabbatar da wannan al'amari) ba ka damar fahimtar yadda m da ikon yinsa, don haka cikin jerin ne tsawo da kuma m events. Kuna hukunta da sake dubawa na marasa lafiya su kansu, wani ya sauri warware daga wahala, sakamakon inganta ingancin rayuwa, amma da wani ya sa da yawa daga mummunan kwaikwayo, da kuma juyayinsu na marasa lafiya basu da wani sakamako.

Wannan magani ne mafi sharri ko mai kyau - kuma kunkuntar tambaya ga wani kayan aiki irin su "Kortef". Babban abu a nan - su dõgara a kan kwarewa da kuma kwarewar da halartar likita da kuma cika da dukan da shawarwari.