Biochemical nazarin Hanyar: description, fasali da kuma sakamakon. Biochemical Genetics Hanyar

Biochemical Hanyar - babban hanya a cikin Biochemistry daga cikin manyan hanyoyin da ganewar asali daga cututtuka daban-daban cewa sa na rayuwa cuta. Yana da wannan Hanyar bincike da za a tattauna a wannan labarin.

bincike da wuraren

Abubuwan da biochemical bincike bincike ne:

• jini.
• fitsari.
• gumi da sauran ruwan jikin mutum.
• zane.
• Kwayoyin.

Biochemical bincike Hanyar damar domin sanin enzyme aiki, da abun ciki na kayayyakin da metabolism a daban-daban jiki ruwaye, kazalika don gane keta a cikin metabolism, wanda sun tabbata ga hereditary dalilai.

labarin

Open biochemical Hanyar A. Turanci likita Garrod a farkon karni na ashirin. Ya yi karatu homogentisuria, kuma a cikin shakka daga cikin binciken, da aka samu sun zama wani nakasar rayuwa, ko na rayuwa cutar za a iya ƙaddara a kan tushen da rashin takamaiman enzymes.

Daban-daban hereditary cututtuka suna lalacewa ta hanyar maye gurbi a cikin kwayoyin halittu da cewa canza tsarin da kudi na gina jiki kira a cikin jiki. Wannan gaji da damuwa da carbohydrate, da furotin da kuma sia metabolism.

babban

Domin nazarin sinadaran abun da ke ciki na asibiti ganewar asali da nazarin halittu da kayayyakin da yadudduka, kamar yadda na iya faruwa a Pathology na taro canji, babu gyara, ko mataimakin versa bayyanar wani bangaren. Domin biochemical analysis m yawa daga wasu abubuwa, hormonal auna, enzymes.

Diddigin kwayoyin, sunadarai, nucleic acid da wasu abubuwa wanda wani bangare ne na wani rai gabar.

sakamakon

Sakamako na biochemical bincike Hanyar za a iya raba ingantaccen (samu ko ba su samu) da kuma gwada yawa (yadda da abun ciki na wani abu a cikin biomaterial).

A ingantaccen hanyoyin da ake amfani da kaddarorin halayyar da abu amfani, wanda ke faruwa a lokacin da wasu sinadaran da tasirinsa (a karkashin dumama, Bugu da kari na reagents).

Direct gwada yawa Hanyar bincike dogara ne a kan wannan manufa, amma da farko ƙayyade ganewa na wani abu, sa'an nan Ya ƙaddara ta maida hankali.

Hormones, shiga tsakani kunshe ne a cikin jiki a sosai kananan yawa, saboda haka su abun ciki da aka auna ta wajen nazarin halittu gwajin abubuwa (msl, dukan jiki ko mutum gwaji dabba). Wannan qara ji na ƙwarai da bayani dalla-dalla da karatu.

tarihi juyin halitta

Biochemical hanyoyin inganta samun mafi m sakamakon da bayanai a kan Jihar tafiyar matakai na rayuwa a cikin jiki, da tafiyar matakai na rayuwa a takamaiman gabobin da kuma Kwayoyin. Kwanan nan, da nazarin halittu bincike hanyoyin hadu da sauran bincike dabaru irin na rigakafi, histological, cytological, da sauransu. Don amfani da ƙarin nagartaccen hanya ko hanyoyin da ake amfani da musamman kayan aiki.

Akwai wata shugabanci biochemical hanya, wanda ba ya haifar da bukatar da na asibiti ganewar asali. Tare da ci gaba da aikace-aikace na mafi m da kuma Saukake Hanyar cewa zai iya ba da damar 'yan mintuna domin sanin bukata kima na biochemical sigogi.

Yau awon sanye take da latest kayan aiki da kuma ci-gaba inji da kuma atomatik tsarin da na'urorin (analyzers) cewa ba ka damar sanin da ya dace kudi da sauri da kuma sosai.

Biochemical nazarin hanyoyin: Hanyar

Ji na wani abu a cikin nazarin halittu ruwaye da su tabbatar da dalilin da aka sanya daban-daban a hanyoyi masu yawa. Alal misali, domin ayyana wani nuna alama a matsayin cholesterol esterase iya zama daruruwan zabin da biochemical bincike hanyoyin. A zabi na da dabara dogara sun fi mayar a kan yanayin da nazarin halittu ruwaye.

Biochemical nazarin Hanyar da aka yi amfani da ƙayyade daya abu ko nuna alama singly kuma a kuzarin kawo cikas. Wannan nuna alama aka bari a wani lokaci na rana, a karkashin takamaiman kaya, a cikin cuta tsari, a lokacin da samun wani magunguna.

Features na hanyar

Features biochemical Hanyar:

• da mafi ƙarancin adadin da biomaterial.
• gudun da bincike;
• da zai yiwu a maimaita yin amfani da da hanyar.
• daidaito;
• biochemical Hanyar za a iya amfani da a cikin shakka daga cutar.
• shan magani ba ya shafar da binciken sakamakon.

Biochemical hanyoyin jinsi

A halittar jini, da aka fi amfani Hanyar for cytogenetic karatu. Yana ba ka damar nazarin daki-daki, tsarin da chromosome da karyotype. Tare da wannan hanya shi ne mai yiwuwa a gano da kuma monogenic hereditary cututtuka cewa unsa maye gurbi da polymorphisms kwayoyin halitta da kuma wa gininsu.

Biochemical Genetics Hanyar yanzu yadu amfani a sami sabon siffofin mutant alleles a cikin DNA. Ta hanyar wannan hanya shi aka gano da kuma bayyana fiye da 1000 domin wannan rayuwa cututtuka. Mafi yawa daga cikin cututtuka da aka bayyana - suna cututtuka cewa suna hade da lahani a cikin enzymes da kuma sauran tsarin sunadarai.

Ganewar asali na rayuwa cuta da biochemical hanyoyin da aka gudanar a matakai biyu.

A mataki na farko:

• ance zargi da laifi lokuta.

A mataki na biyu:

• mai ladabi ganewar asali da cutar mafi m da kuma rikitarwa hanya.

Jariri jariran a cikin prenatal lokacin da taimakon biochemical hanyoyin yin ganewar asali na gaji cututtuka cewa tsiraru da tabbatar da farkon ganewa na Pathology da kuma fara jiyya a lokacin.

iri Hanyar

Biochemical Genetics m iya samun dama iri iri. Dukan su kasu kashi biyu kungiyoyin:

1. Biochemical hanyoyin, wadda ake bisa ganewa na wasu biochemical kayayyakin. Wannan shi ne saboda canje-canje a cikin ayyuka daban-daban na alleles.
2. A hanya, wanda ta dogara ne a kan gaskiyar to kai tsaye gane ƙẽƙasasshen nucleic acid da sunadaran da gel electrophoresis a hade tare da sauran dabaru irin su Southern shafe hybridization, autoradiography.

Biochemical Hanyar taimaka wajen gano heterozygous dako na cututtuka daban-daban. Mutational matakai a cikin jikin mutum kaiwa zuwa bayyanar alleles da chromosomal rearrangements, waxanda suke da sharri a gare mutum kiwon lafiya.

Biochemical bincike hanyoyin iya gane daban-daban polymorphisms kuma gene maye gurbi. Inganta biochemical hanyoyin da biochemical ganewar asali na lokacin mu taimaka a gano kuma a tabbatar da dama daban-daban cuta na tafiyar matakai na rayuwa ta jiki.

Wannan labarin da aka sake nazari ta biochemical analysis.