Antivirals

Antiviral kwayoyi - kwayoyi da cewa aiki a kan ƙwayoyin cuta ta tareda žata wa gininsu ko rashin lafiya m ayyuka.

A halin yanzu ɓullo da wani isasshen yawan irin kwayoyi. Dukan su suna classified da halaye na pharmacological ayyuka da kuma ga takamaiman likita alamomi. Ware wadannan gungun na antiviral jamiái: baza bakan antiherpethetical, protivotsitomegalovirusnye, mura, anti-retroviral. A mafi sani wakilan na farko da irin kwayoyi ne "ribavirin" da "Lamivudine". Wadannan kwayoyi da hadaddun sunadaran da mataki, alaka da rage na nucleic acid da dauri ga enzymes daga cikin cutar. Kamar yadda sunan filin na aikace-aikace na wadannan kwayoyi ne quite m da ya hada da mutane da yawa DNA - da RNA-dauke da ƙwayoyin cuta da cewa sa da PC ta ciwo, zazzabin Lasa, hepatitis C, da kuma AIDS.

Antiherpethetical kwayoyi suna wakilta hudu kudi, wanda ta hanyar su morphological tsarin nucleoside analog acyclovir, penciclovir, famciclovir, valacyclovir. A karshe biyu sashi siffofin ne m. A cikin mutane, suna tuba zuwa acyclovir da penciclovir. Wannan sa su kusa morphological da histological Properties.

Ginshikai na mataki na acyclovir ne a hulda da kwayar enzymes, sa'ilin tarnhayar su ci gaban sake zagayowar. A sakamakon haka ne halakar da pathogen. Wannan hulda da aka bayar da tsarin acyclovir, wanda shi ne wani analog dezoksiguanedina (purine nucleoside). Mai kula da miyagun ƙwayoyi ne herpes simplex cutar. Akwai damuwa da kwayoyin da suke resistant ga wannan miyagun ƙwayoyi. Wannan sakamako za a iya bayyana ta hanyar yin amfani da immunosuppressive far. Ginshikai na adawa ne maye gurbi da cutar enzyme tsarin, canza bayani dalla-dalla na da miyagun ƙwayoyi. A taron na irin wannan yanayi ne kwayoyi na sauran pharmacological kungiyoyin ( "Foscarnet"). Yara antivirals hada da "Valacyclovir." High bioavailability, wanda shi ne fiye da hamsin bisa dari na haddasawa irin wannan sakamako. Wannan yana nufin cewa shi bukatar da yawa karami allurai da miyagun ƙwayoyi (idan aka kwatanta da "Acyclovir") a cimma sakamako.

Ginshikai na mataki na penciclovir kusan babu daban-daban daga cikin shirye-shirye na kungiyar. Yana kuma warware da kira DNKmikroorganizma. Duk da haka, shi ya bambanta a cewa sun fi mayar da rinjayar da Varicella-Zoster virus (VZV).

By protivomegalovirusnym kwayoyi hada da "Ganciclovir", "Valganciclovir", "Foscarnet", "Cidofovir", "Fomiversen". Bã su da wani m rikitarwa inji na mataki, wanda ya shafi m hanawa na DNA polymerase na kananan kwayoyin. A sakamakon wannan hulda ne contravention na elongation na DNA sarkar da take kaiwa zuwa ta mutuwa. Mai antiviral da kwayoyi da kawar da cututtuka na cytomegalovirus kamuwa da cuta - yana nufin wannan pharmacological kungiyar. Duk da haka, bayan tsawo da yin amfani da miyagun ƙwayoyi juriya iya ci gaba, wanda da ɗan rage kewayon su amfani.

Antiviral kwayoyi na iya samun tasiri kai tsaye a kan mutum immunodeficiency cutar. Saboda haka, wasu magunguna, wanda yana da irin wannan mataki, a hade maganin kungiyar. Su duka suna da wani hadadden tsari na mataki da ake dangantawa da blockage na enzyme tsarin da kwayoyin, ta kwafi take hakkin.