Patau ciwo

Patau ciwo ne classified kamar cututtuka da chromosome kafa gwada yawa Pathology. Domin wannan cutar halin da ake kira trisomy - gaban wani karin chromosome goma sha uku.

Chromosomal yanayin da cutar da aka fara gano a 1960 by Dr. Klaus Patau, bayan wanda aka mai suna. A cuta yana da wani sunan - "Trisomy 13". Its ya faru ne daya hali ta 5 - 7000 jarirai. A cuta bincikar lafiya tare da daidaita mita a duka biyu mata da maza.

A ci gaba da wannan cuta saboda nondisjunction na chromosomes a lokacin meiosis (aiwatar da cell division, alhakin wani karu a yawan 'yar Kwayoyin chromosomes). A sakamakon keta da wannan tsari a cikin wani chromosomal bayyana goma sha uku karin chromosome, wanda shi ne tamkar hanyar pathological canje-canje da cuta daga tayi.

Don kwanan wata, da chromosomal ka'idar gadar hali ba tabbatar da cewa cutar za a iya daukar kwayar cutar daga tsara zuwa tsara. An yi imani da cewa wani take hakkin da aiwatar da rabo daga chromosomes da su nondisjunction - bazuwar taron cewa ya faru a lokacin da hadakar da kwayoyin sa na maniyyi da kwai a ganewa.

An lura da cewa hadarin da tayin da wannan cuta ke tsiro muhimmanci tare da kara shekaru uwãyensu ne. Bugu da ƙari, akwai bincike da sakamakon da ya tabbatar da yiwuwar wannan chromosomal anomaly karkashin mataki na radiation.

Mutane da yawa chromosomal cututtuka sa lamba chromosomal munanan ne isasshe musamman na asibiti manifestations. Wannan ya sa ya yiwu don gane asali cutar ko ba tare da ƙarin bincike - a cikin bayyanar da jariri. Patau ciwo yana nufin musamman don wannan cuta, da kuma halin da mahara nakasar malformations.

A jariri da ciwo Patau, ya lura da wadannan haihuwa lahani: craniofacial munanan - microcephaly, quntata palpebral fissures, kananan-sized idanu, corneal opacities, beveled low goshi, sunken hanci, kogon lebe da kuma palate, kazalika da polydactyl anomalies daina cin .

Kusan ko da yaushe a jarirai da Patau ciwo ana gano hanji malformations na tsakiya m tsarin, kodan, zuciya, al'aurar. Shafi yara da wahala daga wani nauyi, shafi tunanin mutum retardation, convulsive ciwo, hypotonia tsoka.

A kan tushen da na asibiti manifestations cewa faye hali Patau ciwo, da farko ganewar asali ne sanya gani, nan da nan bayan haihuwa. An duban dan tayi scanning damar visualizing ciki lahani, da kuma bincike na chromosome quantification tabbatar gaban chromosomal munanan.

Yawancin yara kamu da Patau ciwo mutu a cikin watannin farko na rayuwa saboda su da ciwon mafi tsanani malformations kusan dukkanin kayan ciki. Kaɗan daga gare su tsira zuwa ga na farko da ranar haihuwa. Duk da haka, wasu marasa lafiya rayuwa ga dama shekaru, a gaskiya, tare da dace kula da kuma gudanar da isasshen magani tsawon rayuwar wadannan yara ne ya karu zuwa 5 - 10 shekara. Duk da haka, duk suka yi ayan sha daga babban shafi tunanin mutum retardation - idiocy.

Amma ga likita kulawa, shi ne yawanci directed kawai don kawar da physiological matsaloli. An kullum da za'ayi m gyara na pathological canje-canje na ciki gabobin domin ya kula asali rayuwa ayyuka, kazalika da roba lebe da kuma palate. A sauran misalta zalla symptomatic magani, rigakafin cututtuka da kuma colds, meticulous kulawa.