Mene ne tsawon lokaci na platelet rayuwa? platelet lifecycle

A kan aiwatar da degeneration na sel a cikin bargo, platelets suna kafa. Waɗannan su ne Kwayoyin alhakin coagulation aiki na jini da kuma ga maido da jijiyoyin bugun gini katangu.

balagagge jihar

Magana ne game da abin da rai span na platelets, mafi masana la'akari kawai da lokacin da aka gano a matsayin mai raba tsarin daga megakaryocyte. A lokaci a lõkacin da suka kawai kafa da kuma balagagge, ba ɗauke shi zuwa lissafi.

A kan talakawan, su ne a cikin jini for game da mako guda. Amma da rayuwa Hasashen na mutum platelet iya Range daga 5 zuwa 12 days. Masana sun gano da yawa daga jinsunan: matasa, da haihuwa, balagagge kuma nau'i na hangula. Ba su dogara a kan shekaru daga cikin sel da halaye na aikin hematopoietic tsarin.

A sake zagayowar na ci gaba

Duk da platelets aka kafa a bargo. Yana fara da mallaka-kafa naúrar megakaryocyte, shi ne ake kira "CFU-Meg." Yana da aka raba ta mitosis. Domin shi ne kafa da farko promegakarioblast wanda ya wuce a cikin megakaryoblasts.

Domin 4-5 days a cikin bargo girma musamman Kwayoyin - megakaryocytes, wanda diamita ne game da 60-120 microns. Wadda ta gabãta daga na musamman nau'i na hatsi-free basophilic cytoplasm da kuma tsakiya hali ya polymorphism. Shi ke kira "promegakaryocyte". A balagagge megakaryocyte cytoplasm ne manyan a size da kuma samuwar hatsi a ta Violet-m launi. Da zuciyar shi m, shi yana iya zama daban-daban m siffofi.

An rabu da cytoplasm megakaryocyte kananan maikacin jini, da kamã da siffar wani faifai. Daga wannan lokaci za mu iya magana game da abin da duration na rayuwa na platelet. Tantance, kamar yadda mai mulkin, kawai balagagge siffofin. Su ne a cikin jiki da lafiya mutum ya zama game da 90%.

Yawan Kwayoyin

Don fahimtar me ya sa irin wannan taro a cikin jinin da ba na nukiliya Kwayoyin, shi wajibi ne don ba su sani ba kawai game da abin da duration na rayuwa na platelet, amma kuma game da yadda azumi da kuma yadda da yawa su bayyana. Ga kowane kilogram na jiki nauyi da suka yi zama na domin na 15x10 ^6. Daga kowane megakaryocyte a fission aiwatar otshnurovyvaetsya game da 3000 platelets. Har yanzu game 7-17% na jimlar yawan da aka kafa a cikin huhu. Wannan shi ne saboda a matsayin prothrombocytes shiga cikin jini. Su da kansa isa microcircular haske tashar. Kuma a da shi ya auku platelet saki tsari.

Kowace rana a cikin jikin mutum samar game da 66 ± 14,6 dubu. Platelets da .mu.l na kowane jini. A cikin jini na adult ya kamata mutum ya ƙidaya daga 180 zuwa ⁹ 320h10 wadannan da maikacin jini, da yara na iya zama daga 150 zuwa 450h10 ^9. Amma lokacin da kirga yawan da shekaru kamata a yi la'akari. Alal misali, jarirai da suke ba ko da kwanaki 10, za su iya zama daga 99 zuwa 420h10 ^9.

bayyanar faranti

All balagagge sa da wannan tsarin. A wannan yanayin, da jini platelet rai span iya bambanta. Kowace daga cikin Disc-dimbin yawa faranti ba ya dauke da zuciyar, amma yana da wani tsakiya located granulomer, wanda ya kunshi azurophilic granules. Suna iya zama kamar yadda da yawa daga 5 zuwa 20. Har ila yau, balagagge platelets suna bambanta da gaban da Lilac gialomeru bayyana iyakoki.

A diamita da cikakken cell ne game da 3-4 microns. Suna halin wani m ko madauwari faifai-kamar siffar. A surface a sauran su santsi. Amma a lokacin da a lambar sadarwa tare da sauran gawawwakin ko waje surface a cikin Kwayoyin nan da nan ya bayyana threadlike appendages cewa ba su da wani star-dimbin yawa.

tsarin

Bugu da kari ga bayanai cewa talakawan tsawon rai na platelets ne game da 7 kwanaki, yana da muhimmanci a san cewa a kowace cell akwai uku yadudduka. A gefe zone kunshi nadmembrannoy yanki, wanda ya ta'allaka a cikin manufar platelet kunnawa. Bayan shi ne matattarar cewa shi ne alhakin isasshen kuma dace dauki na cell, da kuma jini clotting dalilai. An ake kira phospholipid matrix. Wannan shi Forms koagualyatsionnye gidaje. Shi ne kuma ke da alhakin mannewa da kuma tari na platelets.

A sashi na Sol-gel ne mitochondria. Har ila yau, akwai na musamman tashoshi da cewa connect da Layer tare da matsanancin membrane. Zone Sol-gel qunshi trombostein alhakin da Disc-dimbin yawa faranti.

Dabam, masana bambanta da wasu gabbansa shafin. Akwai 4 iri katsin. A cikinsu ne tsari na jari na dalilai na jini clotting. Su aiki a kowane lokaci, ko da kuwa da cewa tsawon lokaci na platelet rai span ne 5-12 kwanaki.

Ya ce rabuwa zones za a iya daukan a mahara magnification karkashin madubin da Kwayoyin.

platelet lifecycle

Bayan jini platelets da aka rabu megakaryocytes, suka shiga cikin jini. Ya kamata a lura cewa da tsari na wannan tsari da aka thrombopoietin. Wajibi ne ga al'ada platelet samuwar kuma cikakken maturation na cytoplasm na megakaryocytes.

Aƙalla 1/3 daga cikin jimlar adadin ajiye a cikin baƙin ciki. Sauran 70% na jimlar zagawa da jini. Irin wannan daffo aka halitta a cikin baƙin ciki saboda gaskiyar cewa suna motsi a cikin jiki a hankali. Tsari nassi game da daukan 8 da minti. A sakamakon haka, da platelets aka saki a cikin jini da kuma matsawa zuwa inda ake bukata. Duk da matsalolin da baƙin ciki suna nan da nan nuna a kan yawan jini platelets. Duk da haka, wannan ba zai tasiri a tsawon lokaci na rayuwa da platelet, kuma ya canjãwa kawai adadin da jini. Saboda haka, a cikin kau da baƙin ciki, su maida hankali ne muhimmanci mafi girma. Amma tare da splenomegaly (kara girma na jiki), wadannan kananan Kwayoyin motsawa ta da shi sannu a hankali. Wannan take kaiwa zuwa wani gagarumin raguwa a yawan su a cikin jini.

Ya kamata a lura da cewa matakai da hannu a jijiyoyin bugun gini maimaitawa, rauni tsokoki da jini coagulation kawai kananan ƙunshi juzu'i na platelets. A wasu mutu a cikin bargo, saifa, da hanta ƙarƙashin rinjayar macrophages.