Medicine 'Methotrexate'. umurci

Medicine "Methotrexate" umarnin amfani da anti-metabolites category, pyrimidine analogs. Kamancin: "Zeksat", "Treksan", "Triksilem" da sauransu.

Na nufin "Methotrexate" (Allunan) an yarda su kasance gudanar a matsayin wani guda wakili ko matsayin wani ɓangare na hadaddun jiyyar cutar sankara.

By alamomi sun hada da sankarar bargo myeloblastic da lymphoblastic, myelogenous cutar sankarar bargo na kullum ya kwarara a baya mataki, lymphosarcoma. Kamar yadda wani ɓangare na wani Hadakar himiolecheniya magani "Methotrexate" jagora ya bada shawarar ovarian ciwon daji, huhu, nono.

A hakan allurai (yayin da samun filinata alli) miyagun ƙwayoyi wajabta osteogenic sarcoma, Ewing ta ƙari, choriocarcinoma igiyar ciki sarcoma na taushi da nama.

Halitta (allura) da ake amfani da su taimaka cututtuka na psoriatic fata raunuka.

Na nufin "MTX" a cikin sinadaran tsarin (mai amfani ƙunshi irin wannan bayanai) kusa da folic acid a wannan yana da kishiyar sakamako. Kamar yadda wani antimetabolite antagonist da kuma samar da antifolievym sakamako, da miyagun ƙwayoyi slows saukar cell division, ci gaban rayayye proliferating kyallen takarda, bargo da. A medicament "MTX" na taimaka wa slowing ci gaban da m neoplasms.

A magani aka wajabta a ciki.

A cikin hadaddun jiyya na da miyagun ƙwayoyi "Methotrexate" manual bada shawarar fara tasawa zuwa 0.03 grams sau biyu a mako. Ga yara da kashi da rana - 0.02 grams da square santimita na jiki surface area.

Duration na lura - har zuwa makonni biyu.

M shakka ya shafi nada wani adult kashi 0,02-0,025 grams kullum. Duration na lura - har zuwa kwanaki biyar.

A cikin shakka shan magani "Methotrexate" manual bada shawarar ya dauki hutu a daya ko biyu makonni.

Magani contraindicated a immunodeficient jihohin, cutar hanta, thrombocytopenia, leukopenia, anemia (ciki har da aplastic da apoplastic) hypersensitivity.

Bai isa ba data gudanar da warkewa darussa na magani "Methotrexate" ciki da kuma lactating. A dangane da wannan magani a cikin antenatal lokaci da kuma a lokacin lactation ba su rababbe.

Akwai da kwayoyi "Methotrexate" illa. Da miyagun ƙwayoyi zai iya sa gagging, tashin zuciya, zawo, da ciwon kumburi a cikin baka mucosa (stomatitis). Tsawo amfani da kwayoyi "MTX" alama rauni tare da zub da jini a cikin baka mucosa na ulcerative hali, rage platelet kirga, gashi hasara, rage haemoglobin abun ciki a cikin jini. A wasu lokuta, secondary kamuwa da cuta za a iya lura, wata ila ya sa guba hepatitis (yawanci a lokacin da ake ji hakan allurai), koda raunuka.

Domin kauce wa ci gaban da a ke so sakamakon da warkewa Hakika shi ne da za'ayi a karkashin tsauraran dubawa na likita.

A hali na yawan abin sama ba gyarawa musamman manifestations. Diagnosing da yanayin da aka za'ayi da abinda ke ciki na miyagun ƙwayoyi "Methotrexate" jini.

tsõratar

A kayan aiki da ba a amfani a cikin pleural effusion, ascites, ulcers, ulcerative colitis, koda cuta ko gout.

Kada ku riƙi magani varicella (ciki har da kwanan nan canjawa wuri ko bayan hulɗa da mai cutar), herpes zoster da kuma sauran m cututtuka na dauke da kwayar cutar asalin.

A farkon da kuma a cikin hanya na lura shi ne zama dole don sarrafa gefe jini hoto, hanta da koda aiki.

A da ake ji da miyagun ƙwayoyi a psoriasis ko rheumatoid amosanin gabbai, cikakken jini count sanya a kalla sau daya a wata.

A lokacin da gudanar da bincike an gano mutagenic da carcinogenic effects magani "Methotrexate".