An autoimmune cuta ne thrombocytopenic purpura

A karo na farko da wani autoimmune thrombocytopenic purpura, aka bayyana a cikin 1735 Verlgofa wanda ya lura da cuta a cikin shekaru goma 'yarinya. A halin yanzu a karkashin wannan sunan form hada autoimmune thrombocytopenia, dalili autoaggression a wadda ta kasa. Sun bayyana hemorrhagic diathesis da ya zama ruwan dare rashi na platelets. Ware m kuma na kullum nau'i na cutar.

Sanadin

M thrombocytopenic purpura sha mafi yawa yara shekaru 2 zuwa 9 shekaru. Thrombocytopenic purpura a yara ne halin kwatsam farko da m dawo. Development na asibiti manifestations sau da yawa inganta kwayar cutar daga cikin manya na numfashi fili ko narkewa kamar fili. A 10% na lokuta da cutar hade da ci gaban varicella cutar, Epstein-Barr cutar, allurar rigakafi, BCG immunotherapy. Platelet halaka saboda da rigakafi da martani da kwayoyin maimakon aikin da cutar.

Kullum siffofin thrombocytopenia zaunanniya fiye da 6 watanni ne ake kira idiopathic thrombocytopenic purpura. A sabili da cutar ba a sani ba. Thrombocytopenic purpura sau da yawa fara a samartaka, lokacin balaga. More kowa a mata.

Clinical bayyananen bayyana a hankali. Halin da chronically-maimaituwa ko tsawo hanya da cuta. Pathogenetic tushen cutar heightened da kuma kara platelet halaka ta autoantibodies da su.

asibiti hoto

A cikin fata da marasa lafiya da cututtuka na microcirculatory jini irin yadda punctate petechial rash kananan subcutaneous hematoma, purpura a baka mucosa. Halin da zub da jini na mucous membranes na hanci, gumis. Canje-canje a cikin fata sau da yawa suna located a gaban farfajiya na akwati, manya da ƙananan extremities. Yawanci samuwar manyan hemorrhage a allura shafukan. Lokaci-lokaci akwai iya zama zub da jini a cikin sclera da akan tantanin ido, zub da jini daga narkewa kamar fili. A mata, akwai hemorrhages a cikin ovaries. A tsanani siffofin koda cuta zub da jini na iya faruwa.

Thrombocytopenic purpura iya kai wa ga m rikitarwa kamar cerebral hemorrhage da subarachnoid hemorrhage. Halayyar ne tabbatacce cuff gwajin-Konchalovsky tiller-LEED: samuwar hemorrhages a fata yankunan matsawa. Lymph nodes, hanta da saifa ba a kara girman.

bincikowa da

Babban siffa daga cikin dakin gwaje-gwaje ne don rage yawan platelets. jini clotting lokaci ba keta. Heparin jini an karu. A lokuta da dama, m da karuwa na immunoglobulin G platelets. Bayan gagarumin zub da jini a tsare m hemorrhagic anemia.

magani

Idan kamu da thrombocytopenic purpura, marasa lafiya a fara jiyya da corticosteroids. A lokacin jiyya, marasa lafiya lura wani kwari karuwa a platelet ƙidaya har sai da cikakken gafarta musu. A rashin tasiri na corticosteroids da immunomodulators wajabta delagil. Tare da ineffectiveness na ra'ayin mazan jiya far cikin watanni 6 bayar da shawarar yin splenectomy.

Wani fannin na far - gwamnati na high allurai immunoglobulin ga igiyar jini allura domin 5 days. Wadannan shirye-shirye inactivate antibodies cewa kisa da kuma cire kwayar, kwayan da sauran antigens.

A 80-90% da marasa lafiya a cikin maras wata-wata dawo da faruwa a cikin 1-4 watanni. A wasu lokuta, thrombocytopenic purpura iya wuce har zuwa watanni 12. A cuta ne chronically relapsing: zub da jini lokaci madadin da lokaci na gafarta musu.