Alpha-fetoprotein a al'ada da kuma pathological yanayi

Alpha-fetoprotein ne mai kayan gina jiki asalin wanda aka samar a cikin jakar kwai amfrayo bayan haihuwa - a cikin narkewa kamar fili da kuma a cikin hanta Kwayoyin. Yadda aka saba, shi yana kunshe ne a cikin jiki zuwa 15 NG / ml.

Alpha-fetoprotein aka ƙaddara a lokacin daukar ciki don gane asali lahani da tayin. Yana sami aikace-aikace definition na nuna alama kuma a Oncology. Alpha-fetoprotein ne oncomarker testicular ciwon daji da kuma hanta. A game da 70% na maza da testicular marurai da aka dagagge, musamman a kan aiwatar da metastasis.

Da farko, shi ne mai gina jiki abu hada a cikin ovaries, da ayyukan marubuta luteum. A karo na biyar da ya gabata, da tayin fara samar da nasu. Alpha-fetoprotein kare tayin daga cikin uwa tasa ta rigakafi da tsarin, domin wanda ya ne waje wakili.

Its maida hankali ne ta ƙara a rabo a matsayin tayi jini da kuma masu juna biyu jini. A mafi kyau duka darajar wannan siga ga ganewar asali - at 12-16 makonni. A 32-34 makonni na ciki ya kai matsakaicin matakin na alpha-fetoprotein. m adam na kullum aka samu a cikin shekarar farko ta rayuwa.

Binciken hanyoyin muhimmanci shafi da definition na nuna alama. Kullum yarda nadi munanan na alpha-fetoprotein ya multiplicity na tsakãtsaki ce (inna). A tsakãtsaki shi ne tsakiyar lambar a wani umurni da dabi'u na gina jiki taro a al'ada ciki a cikin wannan lokaci. Saboda haka, wanda zai iya kwatanta alpha-fetoprotein ciki a matakai daban-daban, da kuma ma na nazarin yi a daban-daban dakunan gwaje-gwaje. Matsayin da wannan index daga 0.5 zuwa 2.5 inna ne na al'ada.

Kara AFP na iya zama wani nuni ne na:

• Marurai na bronchi.
• Hanta metastases.
• Ciwon daji na ciki, pancreas, huhu, hanta, ciwon, ƙirjĩna.
• Amfrayo testicular da ovarian siffofin maruran.

Dan lokaci da kuma marginally ya karu alpha-fetoprotein a cikin wadannan pathologies:

• Hanta cirrhosis,
• Kullum hanta gazawar,
• Shan barasa gaban hanta lahani,
• Kullum ko m kwayar hepatitis.

Wannan adadi ya karu a lokacin daukar ciki bayyana a cikin wadannan lokuta:

• Mahara ciki.
• Koda cuta a cikin tayi.
• Cibiyarki hernia a tayin.
• Fetal hanta necrosis.
• Malformations na na tsarin jijiya tube (rahishizis, anencephaly).
• Kogon gaban bango na ciki da tayin.
• Sauran malformations.

Duk da haka, rage alpha-fetoprotein a ciki na iya nuna da wadannan:

• Arya ciki.
• Raya ci gaban da bata lokaci ba.
• Fetal mutuwa.
• Matauni ciki.
• Maras wata-wata zubar da ciki.
• Trisomy na chromosome 18 ko 21.

A rage taro na alpha-fetoprotein iya nuna wani ba daidai ba tabbatar da dalilin da duration na ciki, wato, da ganewa faru daga baya.

A gynecology a yanzu mataki ne na farko aiki nuna alama alama da fetal chromosomal cuta da kuma pathologies daga ciki. Sabawa daga al'ada fetal ci gaba musanyãwa ga al'ada taro na gina jiki da abubuwa a cikin uwa tasa ta jini. Hakika, a can ya zama ba kawai definition wannan nuna alama, kamar yadda shi ne m. Dole bukatar gudanar da duban dan tayi nazarin, sa shi yiwuwa a tabbatar da ta dace definition na lokaci, mahara ciki da sauransu. Har ila yau, shi ne ya zama wajibi a gano kuma a placental hormones (chorionic gonadotropin da estriol free), barin wani cikakken kima na fetoplacental tsarin. Su hade tare da alpha-fetoprotein aka bayyana a cikin sau uku gwajin wanda damar domin sanin hadarin da dama malformations a tayin.