Allunan "fenigidin": umarnin don amfani, real

Mene ne nufi magani "fenigidin"? Umarnin don amfani da na'urar kiwon lafiya, ta contraindications, illa kuma analogs da aka bayyana a cikin daki-daki a cikin wannan labarin. Bugu da kari, za ka koyi a lokacin da ba cikin miyagun ƙwayoyi (alamomi), a cikin abin da sashi ya kamata a dauka, abin da suke faɗa game da shi, marasa lafiya da likitoci.

A abun da ke ciki da kuma tsari da miyagun ƙwayoyi saki

Drug "fenigidin" za a iya samu a Pharmacy a kwaya siffan. Su ne mai rufi da kuma dauke da aiki sashi kamar nifedipine. A sayar da likita wakili ne tsĩrar a cikin wani kartani akwati, inda zai iya zama ko dai katsin 40, ko 50.

Mun kuma yi nazari a kan medicament za a iya kasuwanci kamar wani bayani ga igiyar jini intracoronary ko gwamnati. Wannan magani ya ƙunshi wannan aiki sashi a matsayin kwamfutar hannu.

Pharmacological halaye na kwayoyi

Mene ne magani "fenigidin"? Umurnai na yin amfani da miyagun ƙwayoyi ya furta cewa yana da wani zabe alli tashar shafi aji 2, da kuma dihydropyridine Kalam.

Ginshikai na mataki na wannan magani shi ne cewa shi slows alli ambaliya a sel jijiyoyin bugun gini m tsoka da kuma cardiomyocytes. Magani ne iya exert wani hypotensive da antianginal effects. Yana kuma yana faɗaɗa da na gefe, da jijiyoyin zuciya arteries, lowers sautin na tasoshin, rage hawan jini, na tsari jijiyoyin bugun gini juriya, tsokar contractility, da bukatar na zuciya tsoka na oxygen da kuma rage afterload a kan zuciya. Bugu da kari, da miyagun kwayoyi muhimmanci inganta jijiyoyin zuciya jini ya kwarara.

Allunan "fenigidin" da kadan, ko kuma ba anti-arrhythmic aiki. Haka kuma, ba su depress tsokar madugu.

Pharmacokinetics da miyagun ƙwayoyi

Inda ake tunawa da miyagun ƙwayoyi "fenigidin"? Umarnin a kan aikace-aikace ya furta cewa, bayan da tallafi na alluna a cikin su aiki abu ne hanzari tunawa daga cikin narkewa kamar fili. Da miyagun ƙwayoyi ne metabolized a cikin hanta. Wannan na faruwa a lokacin da "farko izinin", sakamakon samuwar m metabolites.

medicament gina jiki dauri ne kamar 92-98%. A rabin rayuwa yana game 2 h.

Bar miyagun ƙwayoyi abu kamar metabolites a unmodified form (a alamarsu yawa) yafi kodan. Har ila yau, da miyagun ƙwayoyi ne fitarwa ta hanyar hanji (game da 20%).

Alamomi ga yin amfani da magunguna

Idan wani sabawa likitoci rubũta marasa lafiya magani kamar yadda "fenigidin"? A amfani da wannan magani aka nuna a cikin wadannan pathological yanayin:

• domin ya hana shanyewar jiki, ciki har da vasospastic angina.
• domin taimako na angina.
• a hawan jinni crises.
• jijiya hauhawar jini.
• Raynaud ta cutar.

Contraindications da yin amfani da magani

A wasu lokuta, a wani hali ba za a gudanar da haƙuri da miyagun ƙwayoyi "fenigidin"? Umurnai na yin amfani da allunan karkashin shawara ya furta cewa, suna contraindicated a cikin wadannan sabawa:

• a cardiogenic buga.
• jijiya hypotension (systolic jini a lokacin da wani yana da darajar da kasa da 90 mm Hg ..).
• a mai tsanani aortic stenosis.
• a lokacin rushewar.
• a mai tsanani zuciya kasawa.
• idan haƙuri yana da wani karin ji na ƙwarai da aiki kashi kamar nifedipine.

Hanyar na aikace-aikace da kuma sashi daga cikin miyagun ƙwayoyi

Da miyagun ƙwayoyi "fenigidin" da matsa lamba da aka wajabta kawai ga marasa lafiya akayi daban-daban. Domin baka gwamnati da farko sashi na 10 MG sau hudu a rana.

Idan so, da girma na magani ne a hankali ya karu. A wannan yanayin, da sashi zai zama 20 MG sau hudu a rana.

A wasu asibiti yanayi (msl, bambance-bambancen angina, ko mai tsanani hauhawar jini) na wani dan gajeren lokaci da aka yarda su kara da miyagun ƙwayoyi kashi zuwa 30 MG sau hudu a rana.

Don tsara da hawan jinni rikicin, kazalika da angina, da miyagun ƙwayoyi za a iya amfani da ba-baki da kuma sublingually. A wannan yanayin shi ne gudanar a wani adadin na 10-20 MG (da wuya 30 MG).

Domin taimako na hawan jinni rikicin da angina aiki medicament wani lokacin gudanar intravenously (5 MG kan 4-8 hours).

Intracoronary bolus miyagun ƙwayoyi bayani gudanar 100-200 MG. Irin wannan jiyya mafi yawa ana da za'ayi domin kau na m jijiyoyin zuciya jijiya spasms. Jijiyoyin bugun gini stenoses farko sashi ya kamata game da 50-100 micrograms.

A kalla kullum kashi dauke da mu medicament kan ingestion na 120 MG. Domin igiyar jini gwamnati, ta girma kada wuce 30 MG.

Side effects da miyagun ƙwayoyi

Igiyar jini bayani da Allunan "fenigidin" na iya haifar da wani fairly manyan yawan illa. Abin da irin la'akari da a halin yanzu:

• Zuciya da jijiyoyin jini tsarin: asystole, yankin Flushing na fata, tachycardia, na ramin zuciya, abin mamaki na zafi, da kara angina harin, tachycardia, na gefe edema, hypotension, bradycardia.
• Gefe kuma tsakiya m tsarin: tsoka zafi, ciwon kai haske na gani disturbances, paresthesia, barci tashin hankali da kuma tsãwa.
• Narkewa: zawo, tashin zuciya, worsening hanta, hyperplasia na danko. Idan ka yi amfani da miyagun ƙwayoyi domin yayi tsawo da yawa, kuma a high allurai, akwai iya zama dyspepsia, intrahepatic cholestasis kuma dagagge hanta transaminases.
• hemopoiesis tsarin: sosai da wuya ya lura thrombocytopenia da leukopenia.
• Endocrine System: gynecomastia wuya kiyaye.
• Urinary tsarin: kara kullum fitsari fitarwa. Idan ka dauki da miyagun ƙwayoyi na dogon lokaci da kuma a high allurai, akwai iya zama cin zarafi da kodan.
• Alerji: fata da garaje.
• Local halayen: idan ka allurar da miyagun ƙwayoyi intravenously, yana yiwuwa ya kona a allura shafin.

Daya kamata ka manta da cewa minti daya ne bayan intracoronary gwamnati, da mãsu haƙuri iya bayyana korau inotropic effects na nifedipine da kuma kara da zuciya kudi da kuma jini. Wadannan cututtuka bace hankali game bayan 8-15 minti.

miyagun ƙwayoyi hulda da wasu magunguna

Za mu iya, tare da sauran kwayoyi dauki magani "fenigidin Health"? Umarnin a kewaye a cikin marufi, gargadi da cewa mutum kiwon lafiya na iya muhimmanci deteriorate idan muka duba yiwuwar yi amfani da magani yadda ya kamata. A wannan batun, kafin liyafar mu bayar da shawarar ka ka yi shãwara da your likita.

Lokacin da daya-lokaci aikace-aikace na diuretics, antihypertensive jamiái da phenothiazine Kalam iya inganta antihypertensive sakamako na nifedipine.

Tare da lokaci daya amfani da anticholinergic kwayoyi iya sosai da hankali da kuma memory a marasa lafiya pre-ja da baya da kuma ja da baya shekaru.

Idan a lokaci guda dauki da miyagun ƙwayoyi da beta-blockers, sa'an nan da mutum zai iya ci gaba mai tsanani jijiya hypotension, da kuma a wasu lokuta - da kuma zuciya rashin cin nasara.

Tare da na lokaci daya amfani da nitrates qara antianginal effects na nifedipine.

Yarwa liyafar alli da rage-rage yadda ya dace da aiki kashi. Wannan ake dangantawa da wani antagonistic hulda saboda ya karu taro na alli ions a cikin abin da ake kira extracellular ruwa.

Known lokuta da murdede wani rauni, kuma general gajiya yayin da shan miyagun ƙwayoyi da magnesium salts.

Idan ka yi amfani da "fenigidin" tare da digoxin, zai iya rage gudu da kau da karshen daga jiki, wanda sai ya zama dalilin da karuwa da ta maida hankali a cikin jini.

A daya-lokaci kashi na magani da diltiazem kara habaka da antihypertensive sakamako.

Tare da na lokaci daya amfani da theophylline ne iya canza a cikin taro na karshen a cikin jini jini.

Rifampicin abu iya inducing hanta enzyme aiki da kuma hanzarta metabolism na nifedipine, abin da kyakkyawan take kaiwa zuwa wani gagarumin karu a ingancinta.

Idan amfani da miyagun ƙwayoyi a lokaci guda tare da phenytoin, phenobarbital da carbamazepine, chances an rage taro na aiki abu a cikin jini jini.

Akwai da yawa rahotanni na karuwa a nifedipine jini yawa da kuma wani karuwa a cikin AUC a guda aikace-aikace tare da itraconazole da fluconazole.

Idan ka dauki da miyagun ƙwayoyi da fluoxetine, shi ne wata ila don ƙarfafa gefen sakamakon nifedipine a kan jikin mutum.

A rare lokuta, da concomitant amfani da magani tare da quinidine zai iya rage taro na karshen a cikin jini da kuma cire miyagun kwayoyi - muhimmanci ƙara da shi, wanda, ba shakka, taimakawa ga tsawaita na QT tazara a kan electrocardiogram.

Irin wannan aiki abubuwa kamar ranitidine da cimetidine, wani lokacin kara maida hankali nifedipine a cikin jini, kara da antihypertensive sakamako.

Magunguna ƙunshe da barasa ba su ƙãra sakamakon nifedipine, haddasa dizziness da kuma sauran m halayen.

Medicine "fenigidin" a lokacin daukar ciki da kuma lactation

Tsananin sarrafawa da kuma isasshen kariya nazarin da aiki kashi kamar nifedipine a lokacin daukar ciki bai kasance. Saboda haka, yi amfani da wannan magani a lokacin gestation ba da shawarar.

Saboda gaskiya cewa nifedipine aka saki tare da mahaifiyar ta madara, ya kamata ka kauce wa da amfani a lokacin da nono-ciyar da jariri ko yi don dakatar lactation.

A gwaji nazarin saukar embryotoxic, foetotoxic da teratogenic effects na nifedipine a kan mace ta jiki.

Analogs medicament

Da miyagun ƙwayoyi za a iya maye gurbinsu "fenigidin"? Analogues na wannan kayan aiki suna samuwa a duk Pharmacy. Daga cikin su akwai wadannan magunguna: "Adalat", Sponif "," Vero Nifedipine, "" Sanfidipin "," Zanifed "," Osmo-Adalat "," Kaltsigard retard "," Nifecard "," Kordafen "," Nifelat " "Kordafleks", "Nifedipine", "cordipin", "Nifedikor", "Corinfar", "Nifedikap", "Nikardiya", "Nifedeks", "Nifadyev", "Nifegeksal", "Nifebene" da sauransu.

Sanya wadannan kudi kamata kawai likita.

Medicine "fenigidin": reviews na likitoci da marasa lafiya

Masana sun lura da tasiri na da miyagun ƙwayoyi "fenigidin". Yana da sauri sauqaqa angina, kazalika da taimaka tare da hawan jinni crises, Raynaud ta cuta, da kuma hauhawar jini. Duk da haka, a kan wani ɓangare na marasa lafiya, akwai mutane da yawa korau comments game da wannan shiri. A cewar su, shi sa da yawa illa. A mafi akai-akai bayyana ne tsoka aches da juwa. Duk da haka, likitoci sun ce irin halayen ne zai yiwu ne kawai a lokacin da ba daidai aikace-aikace na da miyagun ƙwayoyi. A wannan connection, shi ya kamata a yi amfani ne kawai a karkashin kulawa da wani gwani, musamman a lokacin da haƙuri yana da m tsokar zuciya infarction, mai tsanani take hakki na cerebral wurare dabam dabam, da ciwon sukari, cuta na hanta da kuma kodan, kazalika da m hauhawar jini da kuma hypovolemia.