A hormone 17-OH-progesterone. 17-OH-progesterone: rabon na jini

Babban manufar hormonal sake zagayowar a mata a lokacin hailar sake zagayowar - ovulation. A wannan tsari, shi ne karkashin iko da hypothalamus. A wannan yanayin, da abubuwa kayyade kayayyakin da ake secreted a cikin agara pituitary gland shine yake: FSH da LH.

samuwar ovulation

A cikin pre-ovulatory lokaci na haila sake zagayowar ovarian follicle shigarsu dama canje. Wadannan canje-canje suna faruwa a ƙarƙashin rinjayar FSH. Bayan da follicle kai wani size, kazalika da aikin aiki a LH ovulatory ganiya da aka kafa. Wannan zai kaddamar da "maturation" ovum (na farko meiotic division). Bayan wannan lokaci discontinuity auku a cikin follicle samuwar, da kuma fitar ta hanyar abin da kwai. A tazara tsakanin ganiya kuma ovulation lokaci na domin na 36-48 hours. A lokacin postovulatory lokaci kawar da faruwa yawanci kwai to ya zauna cikin mahaifa na fallopian tube. A cikin hali na hadi da uku-rana ta huɗu, amfrayo shiga a cikin igiyar ciki rami. Akwai ta kafawa. Idan hadi bai faru, to, kwai a lokacin da rana mutu a fallopian tube.

Abubuwa da hannu a cikin rayuwar mata haihuwa aiki

A endocrine gland suna kafa na ilimin aiki mahadi. Su kira ji ba gani. Shi ne da godiya ga su via da hypothalamic-pituitary-ovarian tsarin da kuma tabbatar da akwai ƙwazo aiki na haihuwa gabobin. Kowane fili aikin wasu ayyuka. Daya daga cikin abubuwa da hannu a cikin matakai a cikin haihuwa tsarin, shi ne 17-OH-progesterone. Follicular lokaci gudana tare da wani gagarumin karuwa a cikin taro. Wannan fili an hada a kananan yawa a cikin kwai. Kara da abun ciki na abu ne ganiya mataki na PH. Sa'an nan, a cikin tsakiyar sake zagayowar, da maida hankali ne rage ga wani ajali na. Progesterone a follicular lokaci slows endometrial yaduwa kara kuzari da estrogen. A sakamakon fili ne hõre canji. Babban dalilin da haila ne kwatsam lõkacin fatara daga samar da ayyukan marubuta luteum progesterone sake zagayowar ƙarshe. Wannan wucin gadi tsawo na luteal lokaci endometrial stroma kafa decidual dauki. Yana da kama da canje-canje faruwa a farkon daukar ciki. Progesterone samar da tsari na gland a cikin cervix, rage-rage contractility kogo. A fili ma damuarn haila.

A hormone 17-OH-progesterone. description

Shi ne da precursor steroids. Daga gare adrenal cortisol kafa a ƙarƙashin rinjayar enzymes kamar 11-b 21-hydroxylase ko hydroxylase. 17-OH-progesterone a mata iya haduwa androstenedione. Wannan abu ne mai precursor na testosterone da estradiol. An kafa a cikin ovaries da adrenal gland. A jini progesterone-17-OH ba a free kuma ɗaure da m sunadaran kamar yadda transcortin da albumin. A babu hadi abu taro tayi. A cikin hali na kafawa da kwai a cikin ovaries, da ayyukan marubuta luteum ya ci gaba da samar da shi.

maida hankali

17-OH-progesterone ya karu da safe. Mafi qarancin da abinda ke ciki saukar a cikin dare. A lokacin da rana, da matakin dabam. Kuma fili taro dabam a lokacin hailar sake zagayowar. A gagarumin karuwa a matakin lura da rana kafin LH ganiya. Wannan ne bi da lokaci na matsakaicin maida hankali (tsakiyar sake zagayowar). A lokacin daukar ciki, abu abun ciki da aka muhimmanci karu. 17-OH-progesterone, rabon da wanda aka ƙaddara daidai da shekaru na yara da aka dauke a cikin wani karamin adadin. Manyan yawa ana samu ne kawai a cikin m lokaci da kuma nan da nan bayan haihuwa. A wannan yanayin, a bai kai ba jarirai da abun ciki shi ne gwada da ya fi girma. A lokacin makon farko na connection matakin faduwa. Yana lura da wani m karuwa a lokacin balaga. A wannan lokacin, progesterone-17-OH matasa hankali kai wannan taro kamar yadda a cikin manya.

Don me kuke bukatar wani jini gwajin?

17-OH-progesterone ne tsaka-tsaki samfurin. Duk da haka, ya yi karatu ne wani muhimmin mataki a cikin ganewar asali daban-daban pathologies. By shaidar wani binciken sun hada da rashin haihuwa, hirsutism, sake zagayowar cuta. Lokacin da adrenal hyperplasia a matsayin magani ga marasa lafiya gudanar steroid maye far. Don tantance ingancinta bincike kuma an sanya. 17-OH-progesterone karatu a jarirai. Its taro binciken da ake zargin 21-hydroxylase rashi. Rashi na wannan enzyme lura a nakasar adrenal hyperplasia irin.

Shiri domin awon gwaji

Idan likita ba shi da wani sauran lokaci, da jini ba up a kan na uku zuwa na biyar ranar zagayowar. A binciken da aka gudanar a kan komai a ciki da safe. An ba a yarda da yin amfani da kofi ko shayi. Yarda sha bayyana ruwa. Tun da na karshe ci abinci kafin jini kyauta ya kamata a kalla takwas hours. Masana sun yi la'akari da shi bai dace ba hormone nazari na biyu lokaci a kan 20-23 rana. Idan lokacin kiranka na sake zagayowar na 42 kwanaki, da jini samfurin ne da za'ayi a kan 35 th rana. A kan 23rd rana ta farko zamani har yanzu ci gaba. A matakin na progesterone an rage, amma shi ba ya nuna kasawa na luteal lokaci ko anovulation. Yana sa hankalta da su gudanar da wani binciken na taro a lokacin daukar ciki da kuma dauki wani kwayoyi. A wannan yanayin, wani babban 17-OH-progesterone - da kullum. Irin wannan abun na prenatal kula ba bukata.

fassarar sakamakon

Kamar yadda aka ambata a sama, da al'ada matakin na hormone progesterone, 17-OH dogara a kan shekaru. Muhimmancin da kuma jima'i da batun. A maida hankali ne m, a NG / ml. Mafi kyau duka abun ciki don yara har zuwa wata daya - 0-16,63. 1-2- watanni. - 1,8-9,7. 3 months. - 0,07-1,7. Ga marasa lafiya a karkashin shekara guda - 0-1,65. har zuwa shekaru 3 - 0-0,99. daga 3 zuwa 10 - 0,07-1,69. Halatta matakin for maza - 0.5-2.1. Domin mata a cikin follicular lokaci - 0,41-2,72. ovulatory - 0,33-2,8. luteal - 0,33-2,8. A farko trimester prenatal progesterone-17-OH dole ne su kasance ba a wani taro na 1,17-5,62. Na biyu - 1,17-6,7. a cikin na uku - 1,24-11. A postmenopausal mafi kyau duka abun ciki na 0,13-0,51.

adrenal hyperplasia

Yana da wani nakasar autoimmune Pathology. Yawancin lokaci tasowa a sakamakon rashi na enzymes da hannu a cikin kira na steroids. Rashin mahadi iya daban-daban digiri na tsanani. A ta jariri a nakasar hyperplasia tasowa virilization (samuwar namiji dabiu a mata). A tsanani lokuta, wani enzyme karanci tsokani tsanani take hakki a cikin kira na steroids, gishiri hasara, wanda zai iya zama rai barazana. M rashi na enzyme da aka samu a cikin manya, shi kuma iya zama nakasar a yanayi. A wannan yanayin, da farko take hakki faruwa a latent form, kuma ba su ko da yaushe gano a cikin shimfiɗar jariri. Sosai kira na enzymes iya samun m hali. Ƙarƙashin rinjayar m pathological dalilai qara da yiwuwar samun aikin da morphological canje-canje a cikin adrenal gland, irin wannan manifestations na nakasar ciwo. A sakamakon lalace jima'i ci gaban matasa. A da yawa daga progesterone, 17-OH mayar da hankali ta aiki a kan kira na androgens. Wadannan mahadi circulating a jariri da tsokane 'yan mata magana na jima'i halaye na namiji type. Saboda haka, nazarin ta maida hankali yana da muhimmanci a kayyade da tasiri na magani samu.

A mafi hatsari rashi na enzyme 21-hydroxylase

Rashin fili farfado rage aldosterone samuwar. Wannan adrenal hormone samar da tsari na ruwa da kuma gishiri balance, jinkiri a cikin jikin gishiri. A jarirai, akwai wani "rikicin hasarori." Domin irin wannan yanayin halin da jari na ruwa a cikin manyan yawa. A daidai wannan lokaci na jiki zuwa rayayye janye dole gishiri. A sakamakon haka, da potassium abun ciki fara ƙara, kuma sodium - ƙi. M enzyme insufficiency halin sharewa asibiti hoto. Tuhuma na rashi bayyana a bango na take hakki na mafarki da kuma girma a mafarki, a wani mazan shekaru - tare da rashin haihuwa da kuma sosai a lokacin hailar sake zagayowar, da 'yan mata - tare da hirsutism.

ƙarshe

The aiki na jima'i hormones ne daya daga cikin kayyade dalilai ne ba kawai aiki na haihuwa tsarin a mata. A dauki na mahadi, su kwanciyar hankali da kuma al'ada aiki, sa hannu a daban-daban matakai, kazalika gaban wani mafi kyau duka taro yana da wani tasiri a kan sauran ci gaba na jiki da kuma kiwon lafiya a general. A kwararru gargaɗi da cewa wani sabawa daga data kasance nagartacce a magani ne ba ko da yaushe wata ãyã daga Pathology. A wannan connection, a kowane hali da shi ba ya bukatar magani. Duk da haka, likitoci bayar da shawarar a kai a kai gudumawa da jini da dakin gwaje-gwaje bincike, auku Nazarin. Wasu cututtuka da latent tsari da kuma untimely ganewar asali take kaiwa zuwa tsanani sakamakon. Na musamman muhimmancin ne jihar hormonal mata. Ba gano a cikin shimfiɗar jariri, da cuta da shekaru progresses, haddasa katsalandan a cikin aiki na haihuwa da sauran tsarin a cikin jiki. A wasu lokuta, rashin haihuwa - daya daga cikin mafi gaggawa da matsaloli a yau - shi ne sakamakon marigayi ganewar asali. Ga marasa lafiya da samun sauyawa far, kuma bukatar yau da kullum rajistan shiga-rubucen da jini gwaje-gwaje. A sakamakon damar ba kawai don tantance warkewa inganci daga cikin kwayoyi, amma kuma ya daidaita su aikace-aikace makirci.