"Budesonide": umarnin don amfani da analogues. "Budesonide" inhalation: reviews, farashin

Asma mukamansu farko a duniya daga cikin cututtuka dangantawa da Hyperactivity na rigakafi da tsarin. Don bi shi halitta mai babbar adadin kwayoyi. Wata irin wannan kayan aiki ne "budesonide". Analogs wannan magani ne ma sau da yawa amfani da magani daga broncho-obstructive ciwo. To, abin da yake wannan magani?

Mene ne "Budesonide"?

Wannan magani nasa ne a rukuni na inhaled glucocorticoids. Wannan kayan aiki ne mai roba analog hada a jikin mu (a cikin adrenal bawo) hormones. Wane irin sakamako yana da "Budesonide"?

Umurnai na yin amfani da miyagun ƙwayoyi nuna cewa wakili qara adadin aiki beta-adrenergic rabe a cikin Airways.

Bugu da ƙari, da miyagun ƙwayoyi tubalan da mataki na kumburi prostaglandins da leukotrienes, ta haka ne hana ci gaban kumburi a Bronchial mucosa.

Yana exerts makamantanta bayan kullum gwamnati a kan da dama kwanaki (yawanci game 5-7 kwana).

Shi ne daya daga cikin babban kwayoyi ga zalunta mai tsanani Bronchial fuka da kuma na kullum obstructive na huhu cuta. A matakin farko na ci gaba da wadannan cututtuka ba tambaya.

To, ta yaya "Budesonide" yana da wani sakamako a kan manufa Kwayoyin?

pharmacodynamics

Da miyagun ƙwayoyi ta hanyar inhalation aikace-aikace, da tunawa daga surface na huhu (daga surface na hanci mucosa kusan kai na tsari wurare dabam dabam).

Matsakaicin jini taro da miyagun ƙwayoyi ne lura a cikin minti 45 bayan inhalation. 85 bisa dari na duk mai shigowa da miyagun ƙwayoyi ta ɗaure zuwa albumin jini sauran part aka excreted canzawa.

Yana da aka sarrafa da hanta. Excreted daga jiki ta hanyar da gastrointestinal fili (a cikin bile) da kuma fitsari.

Marasa lafiya da waɗannan jikuna Pathology kiyaye ƙara jinkirta da miyagun ƙwayoyi a cikin jini, abin da ya sa aka ci gaba da rinjaye na da rikitarwa da kuma yawan abin sama na glucocorticoid ji ba gani.

Yana yiwuwa a yi amfani da miyagun ƙwayoyi a kwamfutar hannu tsari domin lura da tsari connective nama (amma kawai 10 bisa dari na jimlar adadin da miyagun ƙwayoyi da cewa ya shiga cikin gastrointestinal fili iya samun warkewa sakamako).

Yana kuma iya yi amfani ga zalunta wadanda ba mai kumburi cututtuka na hanci mucosa saboda shafe tsawon gida mataki.

alamomi

A wasu lokuta, duk da haka, za ka iya sanya "Budesonide"? Umurnai na amfani lists babban cututtuka a wanda wadannan kwayoyi za a iya amfani da:

• Bronchial asma. A miyagun ƙwayoyi ya zama mashahuri godiya ta zuwa ga anti-mai kumburi sakamako da kuma ikon hana aiki na kumburi shiga tsakani.
• Crohn ta cuta. Domin zalunta da cutar amfani tableted nau'i na da miyagun ƙwayoyi. Da miyagun ƙwayoyi da aka bai wa sa gafarar a m kuma matsakaici siffofin da cutar.
• Jiyya na rhinitis. Yana nuna da aiki na intranasal nau'i na budesonide domin taimako na bayyanar cututtuka na hay zazzabi da rashin lafiyan rhinitis. An kyau kwarai wakili ga zalunta da cuta ne "Budesonide Formoterol".
• Rigakafin komawa da polyposis, hanci mucosa. Da miyagun ƙwayoyi da ake amfani a farkon postoperative zamani. Kusan kashi 95% na lokuta hana sake raya polyposis.

The jera cututtuka ne babban matakai, a cikin abin da nada "budesonide".

Wani lokaci, da miyagun ƙwayoyi za a iya gudanar da su hana ci gaban obstructive cutar huhu. Irin wannan lokuta hada da marasa lafiya da sana'a cututtuka ko aiki a m aiki yanayin. Amma ya kamata mu tuna cewa ko da yin amfani da miyagun ƙwayoyi domin rigakafin, kada mu manta da hankali dosing da miyagun ƙwayoyi, tun in ba haka ba wani babban hadarin don samun matsaloli tare da adrenal gland, da kuma janyewar ciwo glucocorticoids.

A wasu lokuta, duk da haka, ta yin amfani da aka contraindicated?

contraindications

A karkashin abin da matakai da cututtuka, ba su yi amfani "Budesonide"? Umurnai na yin amfani da miyagun ƙwayoyi nuna da wadannan cututtuka:

• Karuwan ji na ƙwarai to da miyagun ƙwayoyi, ko da aka gyara. Hadarin na tasowa angioedema.
• The aiki nau'i na da tarin fuka.
• Cututtuka na numfashi fungal asalin.
• M dauke da kwayar cutar matakai a cikin gastrointestinal fili.
• Mai tsanani hanta insufficiency.
• Yara shekaru.

A duk wadannan cututtuka, da yin amfani da corticosteroids da aka haramta. Wannan shi ne saboda cewa da miyagun ƙwayoyi, ko inganta aiwatar exacerbate ko worsen tafarkinsa. The yara ba zai iya yin amfani da wannan magani, saboda cewa zai iya rushe da physiological samar da glucocorticoid hormones saboda insolvency na adrenal bawo.

Akwai wasu gazawa, a cikin abin da matsananci hankali ya kamata a yi amfani da "budesonide". Umarnin a kan aikace-aikace yayi kashedin cewa sosai a hankali ya kamata amfani da miyagun ƙwayoyi domin mutane tare da hauhawar jini, da ciwon sukari, pheochromocytoma, mugunyar ciki miki da duodenal miki.

gefen sakamako

A halin yanzu babu miyagun ƙwayoyi, da yin amfani da abin da ba zai ba sun ɓullo da wani musamman gefen sakamako. Abin baƙin ciki, "Budesonide" ne ma wani magani da wani fairly manyan bakan da m events na ta aikin.

Idan ka yi amfani da "budesonide" inhalation, babban illa na ta yin amfani da za su zama wani jawabin cuta (dysphonia), hoarseness, bushe baki, tari, paradoxical bronchospasm ci gaba.

Lokacin dauka baki, na iya ci gaba da ciki, juwa ko jiri, kuma irritability.

The zuciya da jijiyoyin jini tsarin iya amsa da gabatarwar "Budesonide" cigaban vasculitis, da karuwa a tsari jini, tachycardia.

Da miyagun ƙwayoyi iya haifar da ƙarin tsanani na gastrointestinal cututtuka - ulcers, pancreatitis. Bugu da kari, shi stimulates da ci gaban dyspeptic cuta.

Yana barnatar da rinjayar da musculoskeletal tsarin. Zai yiwu ga cigaban osteoporosis, myasthenia gravis, hadin gwiwa zafi.

A mafi tsanani gefen sakamako ne Cushing ta ciwo. Yana faruwa saboda gaskiyar cewa a lokacin da samun glucocorticoids rage-rage na kira na da kansa hormones. Idan corticosteroids amfani da na dogon lokaci, da adrenal gland iya kawai gushe haduwa physiological abu da dole shafi kiwon lafiya na haƙuri. Wannan shi ne dalilin da ya sa yana da muhimmanci a hankali saka idanu da kashi samu ji ba gani, kazalika da hakkin ya daina shan su.

sashi gyara

A abin da allurai da ya kamata a gudanar da "Budesonide? Umarnin danganci samar da wadannan dosing regimen.

Amfani da inhalation siffofin "budesonide" dangane da tsananin cutar. A ganiya kashi na fara tasawa ne 200-800 micrograms da rana. A kalla kullum kashi kada wuce 1.5 MG. A yara, da miyagun ƙwayoyi ne contraindicated don amfani, da kuma ta analogs aka sanya a cewar mai tsanani daga cikin akwati.

The baka nau'i na da miyagun ƙwayoyi da ake amfani da 30-60 mintuna kafin abinci. Amfani da har zuwa 3 MG sau 3 a kowace rana. A hanya na lura shi ne baka magani domin game da 2 watanni. The ƙi da miyagun ƙwayoyi ne da za'ayi a hankali don a hana janyewar bayyanar cututtuka.

Intranasal yawanci sanya "Budesonide Iziheyler". A kashi da aka zaba akayi daban-daban domin kowane mutum, dangane da tsananin daga cikin tsari. A kan talakawan, suke amfani da 2-3 saukad da miyagun ƙwayoyi a kowane ƙofar hanci kullum sau biyu. A yara, wannan nau'i na da miyagun ƙwayoyi ne contraindicated. A hanya na lura shi ne don makonni 2.

Hulda da sauran kwayoyi

Wasu daga cikin kwayoyi a lokacin da amfani a tare da "Budesonide" iya rage ta sha. Wadannan kwayoyi hada da hanawa da cytochrome P450. Alal misali, idan ka yi amfani da biyu "budesonide" ( "Pulmicort" - kamar yadda wani analog) da kuma kwayoyi kamar "Ketoconazole" "Erythromycin" na iya rage tukar tumbi daga jini na wani glucocorticoid, wanda shi ne fraught tare da ci gaban da hormonal maye da kuma bayyanar illa da miyagun ƙwayoyi.

Bi-biye na'am "Budesonide" da kuma wasu diuretics ( "Indap") na taimaka wa ci gaban hypokalemia a cikin haƙuri, wanda zai lalle shafi aikin zuciya.

Da dama kwayoyi (msl, antacids - "Almagel") yayin da yin amfani da wani "budesonide" exert a kan juna antagonistic sakamako, Ina nufin ba da damar juna zuwa exert da warkewa sakamako. Saboda wannan, shi ne shawarar yin amfani da wadannan kwayoyi a wani lokaci na akalla sa'o'i biyu (shafi kawai ga na baka nau'i na da miyagun ƙwayoyi).

Amfani da miyagun ƙwayoyi domin inhalation

Tun da magani da aka halitta da farko domin lura da cututtuka na numfashi fili, wajibi ne a fahimci abin da hanyar da ya kamata a ba su ba.

Inhaled nau'i na da miyagun ƙwayoyi halitta quite mai yawa, amma su ne yin amfani da kullum converges a hanyoyi masu yawa.

Da fari dai, wadannan kwayoyi yawanci gudanar yin amfani da wani nebulizer. Wannan inji ba ka damar shiga cikin Airways tsananin dace kashi na magani. Yawancin lokaci bace daya rabo na foda ga inhalation, don ya kama da bayyanar cututtuka da fuka ko COPD.

A saboda wannan dalili, kullum amfani da "Budesonide-yan qasar." Wannan magani an jadadda mallaka da Rasha m. A abun da ke ciki da miyagun ƙwayoyi daukawa a dakatar da (ko foda) "Budesonide". A nebulizer ɗora Kwatancen a cassette da miyagun ƙwayoyi, sa'an nan inspiratory wakili shiga cikin bronchi da kuma huhu.

Da dama kwayoyi suna samuwa a cikin nau'i na wani aerosol, wanda kuma ya ƙunshi "budesonide". Ciniki sunan su iya zama daban-daban daga juna, amma da aiki sashi ne har yanzu wannan glucocorticoid. Idan shan irin wannan magani, ya kamata a tuna da cewa daya kashi na aerosol ƙunshi 0.05 ml na budesonide (yana da muhimmanci a san domin kada su sa wani yawan abin sama na glucocorticoids).

A kudin da miyagun ƙwayoyi

Ganin size na yanzu magunguna kasuwa ne, ba wuya a karba wa kansu, "Budesonide" ga inhalation. Its farashin da ta analogues iya bambanta, amma ya kamata a tuna da cewa duk da wannan a cikin tsarin da babban aiki sashi ne budesonide. The kudin da kwayoyi zai dogara ne a kan wanda ya sa da magani, da kuma ko da shi ne a jadadda mallaka miyagun ƙwayoyi ko Generic kwayoyi.

Ana sayar da maganin na musamman a Pharmacy. Nawa ne kudin "Budesonide"? Its farashin da ta analogues ne wani talakawan na daga 300 zuwa 2000 rubles. A duk ya dogara a kan wanda yake da manufacturer da kuma wanda nau'i na da miyagun ƙwayoyi release. Alal misali, irin wannan magani kamar yadda "benacort" da aka samar a cikin nau'i na capsules da foda ga inhalation. A kan talakawan, koda halin kaka 400 rubles. Birtaniya kwayoyi ne yafi tsada. Alal misali, "Budesonide Formoterol" British masana'antu da aka located a cikin 2,000 rubles, cewa ba kowa zai iya iya. Kawai saya Basulabe kayayyakin, wanda ba su bambanta ba a yi, da kuma masu yawa mai rahusa.

A nazarin an tabbatar da cewa mafi tsada kwayoyi ne kusan babu hanya mafi ƙaranci daga gare su kasafin kudin takwarorinsu. Saboda haka, abin da miyagun ƙwayoyi saya - da zabi na kowane mutum, dangane da bukatun da tsaro.

Reviews na shirye-shirye

Glucocorticoid kwayoyi ya dade da aka yi amfani da mutane da yawa marasa lafiya tare da ciwo na kullum obstructive ko asma. Kusan dukan marasa lafiya mai tsanani nau'i na daya daga wadannan cututtuka da ake sa wa "budesonide". Its analogues zauna a fairly m cell a cikin Littãfin magunguna da wadannan cututtuka, haka sau da yawa ake ji a ko'ina. Wannan magani irin su, misali, "Apulein" "Benakap" "Buderin", riga aka ambata a sama "Pulmicort" da "benacort" da dai sauransu

A cewar da yawa marasa lafiya, wadannan kwayoyi ne mafi kyau a lura da cututtuka na numfashi fili. Quite 'yan mutãne waɗanda bã su sun taimaka da inhalation nau'i na glucocorticoid ko ta hade tare da beta-agonists.

Tare da ta dace magani dosing ya iya cimma wani gagarumin ci gaba a cikin wadannan marasa lafiya. A halin yanzu, mutane da yawa kawai ba zai iya yi ciki na rayuwa da kuma al'ada rayuwa ba tare da yin amfani da wadannan kwayoyi.

Duk da haka, duk da yawa m sake dubawa, akwai wani duhu gefe da miyagun ƙwayoyi a matsayin "Budesonide" - farashin.

Na dogon lokaci akwai wani hali da free saduwa fuka magunguna ga marasa lafiya cikin bukata. Dukan marasa lafiya na iya zo cikin kantin magani, da kuma a kan gabatar da dacewa daftarin aiki don samun free magani ga nasu bukatun.

A halin yanzu, an kuma aikata, amma contingent, wanda kowa na da hakkin yantar da wadannan kwayoyi muhimmanci quntata. Yanzu wadannan kwayoyi ne kyauta kawai mutane da nakasa 1 da 2 kungiyoyin, kazalika da yara. Sauran mutane da saya magani ga nasu kudi. Ganin cewa shirye-shiryen daukan quite mai yawa, ba kowane mutum zai iya iya irin magani.