Benzylpenicillin sodium gishiri: umarnin don amfani. aikace-aikace dokoki

A wannan labarin, za mu magana game da irin wannan shiri a matsayin "Benzylpenicillin sodium gishiri". Umarnin don amfani, alamomi, sashi da kuma shawarwari don amfani da za a rufe a cikin labarin. Bugu da kari, mun yi la'akari da pharmacological kaddarorin da miyagun ƙwayoyi, zai yiwu illa da miyagun ƙwayoyi interactions da sauran magunguna.

TOTALS

A miyagun ƙwayoyi ne an antimicrobial wakili da kuma wani kwayoyin na ga penicillin kungiyar. Benzylpenicillin sodium gishiri da kanta, umarnin don yin amfani da abin da za a gabatar a kasa aka samar da daban-daban fungi.

Kwayoyi a cikin wannan kungiyar da ake amfani da intramuscular gwamnati, effects a kan daban-daban tsokoki da kuma gabobin a cikin abin da jini kai a kananan adadin penicillin. Don da miyagun ƙwayoyi fara da effects a kan kwakwalwa da kuma laka da kuma meninges, subarachnoid gudanar.

Benzylpenicillin sodium gishiri, umarnin don amfani: pharmacologically mataki

A miyagun ƙwayoyi ne tasiri da gram-tabbatacce kwayoyin cuta, da suka hada da:

• staphylococci.
• streptococci.
• pneumococci.
• diphtheria .
• coli Anthrax.
• aerobic (tsira da in babu oxygen) sporulating sanduna.

Bugu da ƙari kuma, da miyagun ƙwayoyi ne aiki da gram korau cocci (meningococcus, gonococcus), spirochetes, actinomycetes da wasu kwayoyin. Penicillin sodium gishiri ne m da ƙwayoyin cuta, rickettsiae, fungi, protozoa.

Drug resistant damuwa staphylococci, wanda suke iya samar da enzyme penicillinase, disintegrating benzylpenicillin. A medicament farfado low aiki a lura da Pseudomonas aeruginosa, hanji kwayoyin da wasu kwayoyin, wanda suke iya ware daban-daban yawa na penicillinase.

Pharmacokinetics

A intramuscular miyagun ƙwayoyi hanzari shiga cikin jini, daga inda aka tsĩrar da su da jiki ruwaye da kyallen takarda. Game da cerebrospinal ruwa, shi ya ratsa zuwa kananan adadin penicillin. Cincirindo a jini bayan ta gwamnati intramuscularly lura bayan 30-50 min. Idan da miyagun ƙwayoyi da aka gudanar subcutaneously, da kudi na sha an rage da kuma matsakaicin yawan abubuwa a cikin jini za a iya lura a cikin awa daya.

Sa'o'i uku bayan allura (subcutaneous ko intramuscular) na benzylpenicillin kawai burbushi kasance a cikin jini. Saboda haka, don kula da wani babban taro na miyagun ƙwayoyi a cikin jiki na dogon lokaci, shi wajibi ne allurar ta kowane hudu.

Lokacin gudanar intravenously, ta maida hankali da miyagun ƙwayoyi hanzari da dama. Kuma yayin da shan baki benzylpenicillin an halaka su da penicillinase (enzyme) da kuma na ciki da ruwan 'ya'yan itace.

Excreted miyagun ƙwayoyi excreted a cikin fitsari.

shaidar

Su ya kamata a hankali karatu kafin nadin da miyagun ƙwayoyi a matsayin penicillin sodium gishiri, umarnin don amfani, sashi da kuma alamomi don amfani. Bari mu fara da karshen. Saboda haka, da miyagun ƙwayoyi An wajabta:

• a cututtuka na huhu da kuma numfashi fili.
• m kwamin na tara cututtuka.
• kwayan endocarditis.
• sepsis.
• cututtuka da kuma kamuwa da raunuka da taushi tsokoki, fata da kuma mucous membranes.
• konewa.
• kumburi da laka da kuma kwakwalwa, mazgovyh konkoma karãtunsa fãtun.
• surkin jini pleurisy.
• peritonitis.
• cystitis.
• Pius da septicemia.
• osteomyelitis.
• diphtheria.
• mulufi zazzabi.
• kabba da ciwon sanyi.
• erysipelas.
• Cututtuka a jarirai.
• Anthrax.
• syphilis.
• actinomycosis.
• daban-daban gynecological inflammations.
• kumburi cututtuka na makogwaro, kunne da hanci.

Sharuddan Amfani da sashi

Dangane da irin ganewar asali far amfani benzylpenicillin sodium gishiri da miyagun ƙwayoyi iya gudanar. Umarnin don amfani, hanya na gwamnati da kuma zai yiwu sashi za a yi la'akari da mu a cikin wannan sashe.

A hanya da miyagun ƙwayoyi jiyya na iya wuce, dangane da cutar, daga 4 makonni zuwa 2 watanni ko ma fiye. Da miyagun ƙwayoyi za a iya gudanar a wadannan hanyoyi:

• Intramuscularly a cikin sama m quadrant na gluteal. A shirye-shiryen da aka diluted kafin gwamnati a distilled ruwa, novocaine ko sodium chloride bayani.
• Igiyar jini - .. kawai a karkashin irin wannan tsanani cututtuka, kamar meningitis, kwayan endocarditis, septicemia, da dai sauransu A miyagun ƙwayoyi ne gudanar kowane 4 hour ko m drip - 30 saukad da minti for 6-12 hours.
• Yana iya ma za a gudanar da endolyumbalno benzylpenicillin sodium gishiri. Umurnai na amfani (da ake ji Hanyar) na samar da wani Hanyar for kumburi da kwakwalwa da kuma laka, ciki har da meninges. Da miyagun ƙwayoyi ne allura sosai sannu a hankali - 1-2 minti.
• Akwai lokuta inda benzylpenicillin amfani ga alura da kumburi foci. Alal misali, lokacin da actinomycosis, fata leishmaniasis, na kullum pyoderma da kuma sauran cututtuka fata cututtuka.
• Tare da inhalations - domin lura da kuma rigakafin cututtuka na huhu da kuma Airways. A saboda wannan dalili, gauraye da benzylpenicillin sodium chloride bayani ko distilled ruwa. Inhalations ba fiye da sau 2 a kowace rana. Zaunanniya daya magani - daga 10 zuwa 30 da minti.
• Haka kuma an allura a cikin pleural ko peritoneal rami a surkin jini peritonitis ko pleurisy.
• A cikin nau'i na wanke, man shafawa, m dressings, lotions da powders - for konewa, raunuka na taushi da nama, da kuma osteomyelitis al.
• Har ila yau, da miyagun ƙwayoyi bayani amfani domin lura da babba numfashi cututtuka da kuma a ophthalmology.

Penicillin za a iya amfani da a far tare da sauran maganin rigakafi da kuma sulfanilamide shirye-shirye. Cikinsa da nufin za su karfafa warkewa sakamako na kwayoyi amfani.

illa

Yana kuma iya samun mummunan tasiri na benzylpenicillin sodium. Umurnai na amfani Notes cewa aka nuna su da igiyar jini gwamnati da miyagun ƙwayoyi mafi sau da yawa.

Amma, da illa hade tare da rashin lafiyan halayen ga miyagun ƙwayoyi. Daga cikin m bayyanar cututtuka lura:

• candidiasis.
• amya.
• zazzabi.
• ciwon kai.
• jin sanyi.
• hadin gwiwa zafi.
• Angioedema.
• eosinophilia.
• daban-daban iri dermatitis.
• zazzabi.
• lymphadenopathy.
• anaphylactic tura - a sosai rare lokuta.

contraindications

Ba dukan marasa lafiya za su iya kusanci far da medicament na benzylpenicillin sodium gishiri. Umurnai na amfani da dokokin gwamnati ta samar da wani yawan contraindications. Daga cikin su:

• rashin lafiyan cututtuka irin urticaria, hay zazzabi, Bronchial fuka, da dai sauransu.;
• hypersensitivity penicillin Kalam.
• m martani ga kwayoyi.
• cuta pathogen juriya ga wata naúrar kashi na benzylpenicillin.

A gabatarwar da miyagun ƙwayoyi endolyumbarnym m haramta a epilepsy.

Pregnancy kuma lactation

Nada a lokacin daukar ciki ne kawai idan amfanin da magani daga mata ne mafi girma daga cikin hadarin m zuwa ta haifa ba. In ba haka ba, da miyagun ƙwayoyi ba a gudanar. hadarin rabo da kuma ingancinsu ne m da halartar likita.

Idan dole, gwamnatin da miyagun ƙwayoyi a lokacin lactation ya kamata a daina nono.

Properties

Drug abu benzylpenicillin sodium gishiri yana da nau'i na fari lafiya crystalline foda da wani m dandano wanda shi ne readily mai narkewa a cikin ruwa.

Da miyagun ƙwayoyi ne sauƙi halaka su da acid, alkalis, oxidizing jamiái, enzyme penicillinase, kazalika da dumama. Yi miyagun ƙwayoyi abu dole ne nan da nan kafin gwamnati.

rigakafi

Da miyagun ƙwayoyi ne gudanar kawai a wani asibiti da likita ta sayen magani da kuma karkashin kulawa. Tare da nassi na far kamata a tuna da cewa kasa kashi benzylpenicillin ko farkon ƙarshe na magani iya kai ga samuwar na resistant damuwa kwayoyin. A taron na juriya ga miyagun ƙwayoyi jiyya da aka ci gaba da sauran maganin rigakafi.

A hali da rashin lafiyan halayen gudanar tare da antihistaminic miyagun ƙwayoyi ne benzylpenicillin sodium. Umurnai na amfani (mataki da miyagun ƙwayoyi a ta wajabta musamman daki-daki) ta sanar da cewa a lokacin da wani haƙuri rashin lafiyan bayyananen far nan da nan ya tsaya.

A wasu kungiyoyin da marasa lafiya (tsofaffi, jarirai, ya raunana da rashin lafiya) su yi juriya ga benzylpenicillin, wanda ya haddasa ci gaban superinfection.

Tare da shafe tsawon amfani, da kwayoyin za a iya suppressed ko jera halaka su da hanji microflora, abu don rage samar da bitamin na kungiyar B. Saboda haka prophylactically ga marasa lafiya sau da yawa wajabta bitamin B1, B12, da sauransu.

Idan, bayan da farkon far ga 3 kwanaki aka ba lura da wani sakamako, shi ne zama dole don zuwa hada magani ko sanya wani sabon kwayoyin.

tsõratar

Kariya sanya mutane da zuciya da kuma gazawar illa koda aiki benzylpenicillin sodium gishiri. Umarnin don amfani kuma ya bada shawarar cewa kulawa ta musamman ba ga waɗanda marasa lafiya da suke gani hypersensitivity zuwa cephalosporins.

Saboda yiwuwar fungal superinfection bada shawarar a rubũta anti-fungal jamiái.

Hulda da sauran kwayoyi

A nada wadanda maganin rigakafi, wanda da bacteriostatic, bactericidal mataki na penicillin rage.

Shiri "Probenecid" yana da wata dukiya don rage tubular mugunya kwayoyin cewa results a wata karuwa a jini matakin na karshen kuma, kamar yadda wani sakamako, kara lokacin cire shi daga cikin jiki.