Acid phosphatase a cikin jini: kafiya, dikodi mai da kudi

Acid phosphatase - wani enzyme cewa accelerates da bazuwar daga kwayoyin a cikin jiki. Tabbatar da dalilin da ta matakin a jini yana da muhimmanci ga diagnosing da kiwon lafiya yanayin. Akwai da dama iri acid phosphatases, wanda raba wani aikin m, amma ya bambanta da yawa daga juna dangane da jiki ta kyallen takarda, chromosomal asali, abun da ke ciki.

TOTALS

Powered enzyme a acidic muhallin, Saboda haka sunan. Acid phosphatase da aka samu a daban-daban tsokoki da kuma Kwayoyin iya located in lysosomes da kuma bayan. The most yawan m cikin prostate gland shine yake, kazalika a sel da wadannan gabobin:

• hanta.
• baƙin ciki.
• bargo.
• maikacin jini (erythrocytes, platelets, macrophages).

A wani m kwayoyin da ayyukan acid phosphatase ne wajen low. Da wakilan da namiji rabin ta matakin kunshi da prostatic phosphatase, da abin da aka hallaka a cikin hanta da jini Kwayoyin. A enzymes daga cikin mace jiki kafa gaba daya hallaka da hanta da kuma erythrocytes, platelets.

Lysosomal acid phosphatase

Yana located in mafi Kwayoyin. Its shortcoming ne autosomal recessive cutar, wanda aka dauke su da sakamakon pathological tafiyar matakai na rayuwa. Symptomatology da cutar bayyana kanta kamar haka:

• intermittent tashin zuciya da kuma amai.
• wani rauni, asarar yadda ya dace.
• ragewan jini;
• a cikin shimfiɗar jariri - opisthotonus (seizures cewa faruwa arching na baya baka, marasa lafiya dõgara a kan surface na gado kawai wuyansa, kuma ƙafãfunsu).
• zub da jini.

Idan enzyme matakin ne kasa kawai a fari da maikacin jini, da marasa lafiya sau da yawa sha exacerbations na kullum cututtuka.

Prostatic acid phosphatase

An dauke da wani alama na ciwon daji matakai prostate. Wannan irin enzyme aka ƙaddara, kuma kamar yadda wani iri alama ruwa a cikin gwaji (fyade). Acid phosphatase ne ya tashe, da kuma 'yan kwanaki bayan tiyata a kan prostate gland shine yake ko biopsy bango.

Ganiya PH nuna alama ga ta dace aiki na enzyme - 4.6. Aiki bayyana na musamman bayan da wani mutum ya kai lokacin balaga.

A halin yanzu, tabbatas da matakin na prostatic phosphatase a matsayin alama da ciwon daji recedes a cikin bango na ƙara sha'awa cikin prostate-takamaiman antigen, wanda shi ne iya tabbatar da kasancewar cutar a farkon matakai na raya kasa. Duk da haka, Manuniya na prostatic acid phosphatase ne mai muhimmanci a cikin tsinkaya da komawa da ciwon daji aiwatar bayan tiyata ga m prostate kau.

A analysis domin sanin tasiri na jiyya na benign prostatic hyperplasia da sauran prostatic pathologies.

eritrotsitarnaja phosphatase

Wannan shi ne wani polymorphic enzyme cewa ba kawai a cikin ja jini Kwayoyin amma kuma sauran Kwayoyin na jiki. A ganiya PH domin ta aiki dabam daga 5.2 zuwa 6.2.

Acidic phosphatase jini za a iya ƙaddara don bayyana ubanci. Wasu siffofin da enzyme suna hade da wadannan yanayi:

• kwayoyin predisposition zuwa hemolytic anemia.
• Pathology, wanda aka halin da ci gaban hemolytic anemia a bango cin legumes.
• anemia a cikin yin amfani da wasu kwayoyi ko tasowa kamuwa da cuta daga kwayar kuma kwayan asalin.

Akwai siffofin erythrocyte acid phosphatase kai tsaye alaka keta cewa faruwa a cikin shimfiɗar jariri.

Macrophage irin acid phosphatase

A enzyme ne mai muhimmanci a cikin ganewar asali Gaucher cuta. Wannan sigar gaji cuta wadda bayyana jari a cikin hanta, saifa, koda, kwakwalwa, huhu glucocerebroside (kwayoyin abubuwa daga cikin rukuni na kitse). Cutar da ake tare da wani gagarumin karuwa a cikin size da muka ambata a sama jikinsu, mai kaifi karu a yawan dukan da maikacin jini, seizures, spastic seizures, shafi tunanin mutum retardation.

Macrophage acid phosphatase kuma dauke da wani takamaiman alama ga m cell cutar sankarar bargo. Wannan cuta yana tare da samar da gagarumin adadi na enzyme, wanda aka ƙaddara a cikin jini.

phosphatase osteoclasts

Kira osteoclasts kashi Kwayoyin alhakin ta hallaka. Wannan mataki ne mai muhimmanci da la'akari da ci gaban kashi da kuma maimaita naúrar. High gudun kashi hasãra tafiya tare da wadannan cututtuka:

• Paget ta cuta (pathological kira al'ada kashi samuwar kuma ta abubuwa);
• hypercalcemia na malignancy.
• Hyperactivity na thyroid da parathyroid gland .
• postmenopause a hade tare da osteoporosis.

Result - m samu karaya kuma m thinning daga kashi Tsarin. Tabbatar da dalilin da acid phosphatase osteoclasts nuna darajar matakan enzymes a bango na sama pathologies.

Shirya da kuma gudanar da bincikowa

Gwada yawa Manuniya an ƙaddara a awon yanayi. A analysis kamata a da za'ayi bayan kwanaki 2 daga lokacin da wasu bincike hanyoyin. Idan kana so ka tantance matakin da prostatic acid phosphatase, wannan ya kamata a yi ba a baya fiye da sa'o'i 48 bayan da biopsy, palpation na prostate, mafitsara catheterization. A daura da haka al'amarin, sakamakon zai iya zama ƙarya galaba.

Shinge abu domin gudanar da bincike da za'ayi a kan komai a ciki. Za ka iya sha kawai ruwa, ya sha, shayi, kofi, juices da sauran abubuwan sha da aka haramta. A lokacin da rana, kana bukatar ka daina giya, m, kyafaffen jita-jita, 1 hour kafin analysis - daga shan taba. A karshe rabin sa'a kafin ci daga cikin kayan dole ne a gudanar a cikin cikakken wani tunanin da natsuwa.

Ga ganewar asali na venous jini da ake amfani, wato ta magani guje wa hemolysis. A binciken da sakamakon da aka sani na gaba rana bayan da binciken.

Hanyar da suke amfani

Don fayyace wannan matakin na jimlar acid phosphatase amfani immunochemical dabaru da chemiluminescent ganewa. Yi amfani da musamman substrates cewa hulɗa tare da wasu enzymes. A halin yanzu tsarin aikin ijãra luminol Kalam peroxidase a hade tare da hydrogen peroxide bayani. Wannan sakamako ne kara Mafarin (msl, n-yodofenol) na iya kara luminescence na mafita ga dama dubu sau.

Akwai sauran tsarin da amfani da alkaline phosphatase da AMPPD substrate, yin bincike Hanyar fi m. Abũbuwan amfãni daga cikin Hanyar ne don nazarin zaman lafiyar na reagents amfani, babu radiological hadarin. Gazawa dangane da wuya daga cikin bincike tsari.

na kullum

Total acid phosphatase kima nuna U / L. Its canja sigogi bambanta dangane da shekaru da kuma jinsi.

Al'ada prostatic acid phosphatase Manuniya - kasa da 2.1 ng / ml. All Figures sama nuna tabbatacce sakamakon cutar.

Lokacin da matakin da enzyme ya karu?

A mafi tsanani da yanayi na wanda gwada yawa matakan sama al'ada:

• thrombocytopenia - a rage yawan jini Kwayoyin alhakin ta clotting.
• thromboembolism - blockage na lumen na babban jijiya thrombus, ware daga jirgin ruwa bango, ko embolus, wanda suke a cikin jini.
• Hemolytic cuta - wata cuta tare da m halakar ja jini Kwayoyin su saki gagarumin yawa na bilirubin a cikin jini.
• m Paget ta cuta - kashi Pathology na'ura a wanda wani rashin daidaituwa tsakanin kashi samuwar da kuma lalata aka gyara a cikin ni'imar da karshen.
• myeloma - m ƙari aiwatar yanayi, wanda aka samu halartar B-lymphocytes, alhakin kira na m Kwayoyin.
• Niemann-sama cuta - hereditary Pathology halin da illa mai metabolism da kuma jari na lipids a cikin manyan gabobin (hanta, saifa, huhu, zuciya, koda).
• 'yan kwanaki bayan tiyata a kan prostate gland shine yake da nama biopsy.

Acidic, alkaline phosphatase - wani rukuni na enzymes alhakin muhimmanci matakai a cikin jiki. Yana da da su taimako fãra m jere halayen. Tabbatas da matakin na enzymes damar lokacin da za a duba samuwar Pathology da kuma kai shi zuwa ga tallafawa gyara na kara high quality na rayuwa.