"Plagril": umarnin don amfani, real likitoci. Drug analogues "Plagril"

Cututtuka na zuciya da jijiyoyin jini tsarin ne a zamani magani watakila a farko wuri. The mace-mace kudi daga wadannan cututtuka ne mafi girma. Akwai matsaloli a cikin wannan yanki da cewa zai iya wajaba a mutum daga lokacin haihuwa. Duk da haka, akwai waɗanda a cikin abin da mutum ya ke ci gaban kawo babba "taimako". Wata irin wannan cuta - atherosclerosis. Idan wannan matsalar yafi shafar arteries m kuma na roba tsoka-type. Jigon da cuta a cikin abin da, saboda keta da furotin da kuma sia metabolism tara a cikin jijiyoyi na cholesterol adibas da kuma wasu yayan na lipoproteins. Kamar wancan kafa atherosclerotic plaques. A tsawon lokaci, da connective nama na jirgin ruwa ganuwar a wadannan plaques fadada, sakamakon shi a takaita da lumen na jijiya har da occlusion.

Domin taimaka wadannan marasa lafiya, da masu bincike sun ɓullo da wani jerin kwayoyi da cewa zai iya rage gudu ko gaba daya kashe da tari tsari (mahadi, bonding) na platelets. Abubuwa da irin wannan damar, an kira antiplatelet (antithrombotics). Wata irin wannan magani ne "Plagril".

Tsari da kuma abun da ke ciki

A miyagun ƙwayoyi ne samuwa a Allunan rufi da wani fim shafi ruwan hoda. A Allunan ne zagaye, biconvex. A gefe daya crammed embossing "C 127". Babban aiki sashi daga cikin miyagun ƙwayoyi - clopidogrel. Ba zato ba tsammani, a wani magani "Plagril" INN (International Nonproprietary Name) ne m ga sunan babban bangaren - clopidogrel. The girma abun ciki da kwamfutar hannu - 75 MG. Bayan da babban aka gyara daga cikin medicament ne excipients: microcrystalline cellulose, mannitol, croscarmellose sodium, colloidal silicon dioxide, magnesium stearate. Masana'antun samar da miyagun ƙwayoyi a bororo fakitoci na 10 guda.

Ginshikai na miyagun ƙwayoyi

Da miyagun ƙwayoyi ne a takamaiman hanawa (hana - hana, kashe wani tsari) tari (fili) platelets. Yana yana koronarorasshiryayuschee mataki. Tsari deceleration platelet tari (game da 40%) za a iya gani bayan 2 hours bayan ingestion na miyagun ƙwayoyi a sashi na 400 MG. Domin cimma iyakar yadda ya dace (60% hanawa na tari) effects daga Allunan "Plagril", umarnin don yin amfani da bisa ga bukatar far ga 4-7 kwanaki. A duka kashi da rana ya zama daga 50 zuwa 100 MG. A wannan yanayin, antiplatelet sakamako zai šauki ga dukan rai sake zagayowar daga platelets (7 zuwa 10 days). A cikin kwanaki 5 bayan miyagun ƙwayoyi karbo kudi na platelet tari, da kuma zub da jini lokaci baya to da farko yi.

Excreted "Plagril" koda da hanji (50% kuma 46% bi da bi). deducing Period - 120 sa'o'i bayan gwamnati.

Babban masu amfani da "Plagrila"

Akwai musamman kungiyar na zuciya marasa lafiya da suke nuna su yi amfani da magani "Plagril". Umarnin da ake bukata domin daukar wani magani ga mutanen da fama da atherosclerosis. Magani ne tasiri a matsayin m gwargwado ga rage hadarin rikitarwa dangantawa da thrombosis a mutanen da suka yi wata tsokar zuciya infarction ko ischemic bugun jini. Shi ne kuma gaskiya ne ga marasa lafiya fama da occlusion (tabarbarewar permeability) na gefe jijiyoyi.

A jummai da acetylsalicylic acid (asfirin) za a iya amfani "Plagrila" domin ya hana thrombotic rikitarwa a wadanda suka sha wahala daga m jijiyoyin zuciya ciwo. Wannan zai iya hada mutane da angina (m form), tare da tsokar zuciya infarction ba tare da kalaman samuwar Q. Za ka iya amfani da miyagun ƙwayoyi a marasa lafiya da suke yi mashi stenting. Jigon da aiki - kafuwa a cikin shafa jirgin ruwa stent (bakin ciki lafiya-meshed karfe tube), wanda shi ne baya inflated musamman balan-balan, game da shi kara da permeability da jirgin ruwa da kuma inganta jini ya kwarara zuwa cikin zuciya.

Sashi: aikace-aikace halaye

Medicine "Plagril" marasa lafiya za a iya dauka da baki, ko da rage cin abinci. A marasa lafiya jurewa tsokar zuciya infarction, ischemic bugun jini ko kafa ganewar asali game da patency na arteries tabarbarewar, da kashi na 75 MG dauka sau daya a rana. Period magani far bayan Q-kalaman tsokar zuciya infarction iya wuce har zuwa 35 days. A ischemic bugun jini, dangane da tsananin daga cikin yanayin, magani iya Range daga 7 kwanaki zuwa watanni shida.

Lokacin da shanyewar jiki a wani m tsari, da kuma tsokar zuciya infarction ba tare da samuwar Q-kalaman ne yawanci wani misali regimen na alluna ne kamar haka: na farko, daya-lokaci loading kashi na 300 MG, bi da 75 MG da rana tare da asfirin (75 zuwa 325 MG da rana). Saboda ci asfirin kara hadarin zub da jini, matsakaicin guda kashi kada wuce 100 MG. Drug magani - har zuwa 1 shekara.

liyafar "Plagril" antiplatelet far an kuma nuna ga m tsokar zuciya infarction. Rubũta kwayoyi dauki a kashi na 75 MG, a cikin rana guda. An shawarar da za a fara jiyya da farko loading kashi a hade tare da acetylsalicylic acid. Zai yiwu a layi daya karɓarsu ga thrombolytics (ko iya ba kai).

Idan marasa lafiya sun tsallaka 75 shekara da iyaka, "Plagril" (kama da clopidogrel ma yarda) da aka nada ba tare da wani na farko loading kashi. Bayan bayyanar da hade magani daga cututtuka da ya kamata a fara a farkon yiwu. A hanya ya kamata šauki akalla 4 makonni.

Zai yiwu gefen sakamakon

A lokacin hanya na lura tare da shiri "Plagril" umurci manual sanar da cewa da dama yiwu illa daga daban-daban da kuma tsarin gabobin.

jini clotting tsarin iya sau da yawa amsa to bayyanar gastrointestinal zub da jini. Kadan akai-akai na iya ci gaba hemorrhagic bugun jini, zubar da jini daga hanci da kuma, in general, da karuwa a zub da jini lokaci. A rare lokuta, na iya bayyana hematomas, hematuria.

Daban-daban nuni daga hemopoietic tsarin. Wadannan sun hada da eosinophilia, neutropenia, thrombocytopenia. Muhimmanci kasa kusantar wajen samar da granulocytopenia, sauki ko aplastic anemia.

A wani ɓangare na tsakiya da kuma na gefe m tsarin iya zama ciwon kai, dizziness, paresthesia, vertigo (asarar balance, tare da wani tunani na juyawa daga abubuwan da suke kewaye da jiki, ko mataimakin versa - jikin juyawa), hallucinations, rikice. Quite rare, amma lokuta da m events faruwa tare da zuciya da jijiyoyin jini tsarin, cikin sharuddan rage hawan jini, vasculitis ci gaba. Bronchospasm da interstitial pneumonitis - wannan yana iya zama wani dauki na numfashi tsarin samun miyagun ƙwayoyi.

Mafi sau da yawa a kan magani "Plagril" (reviews na likitoci da marasa lafiya tabbatar da wannan al'amari) reacts narkewa kamar tsarin. A dauki na jiki da aka bayyana a cikin ci gaban da zawo, dyspepsia, ciwon mara. Kadan na kowa yiwu halayen kamar tashin zuciya da amai, maƙarƙashiya, m gastritis da kuma na ciki da kuma duodenal ulcers, flatulence. Rare amma zai yiwu faru na cututtuka irin colitis, pancreatitis, stomatitis, hepatitis, ƙẽƙasasshen dandano, ci gaban m hanta gazawar.

Osteo-murdede tsarin iya bayyana kanta amosanin gabbai, myalgia. Ko da yake shi ya faru da wuya. Glomerulonephritis iya haifar daga dauki na urinary tsarin. Dermatologists bayar da shawarar cewa a zai yiwu sakamakon wani "Plagrila" ne itching, bullous rash, erythematous rash, lichen planus, eczema. Zai yiwu ga cigaban rashin lafiyan halayen a cikin nau'i na angioedema, anaphylaxis, magani ciwo. Da na kowa illa iya a lura da zazzabi, dagagge magani creatinine.

Da amfani da "Plagrila": abin da ya nemi

Idan na musamman halin da ake ciki ne a ke so antiplatelet tasiri, ko ya kamata su tiyata, ya kamata ka soke magani da "Plagril". Umarnin don amfani da shawarar a yi haka a kalla 7 kwanaki kafin tiyata. Bayan da yarjejeniyoyin da miyagun ƙwayoyi da ta dakatar ba zato ba tsammani fara zub da jini za su bukatar karin lokaci. Marasa lafiya ya kamata a yi musu gargaɗi game da shi, kuma rika sanar da likita game da kowane sabon abu zub da jini. A cikin sha'awa na da mãsu haƙuri a sanar da likita game da magani daga "Plagrilom" a kuma waɗannan lokuta, idan ya zama wani tiyata, ko da haƙuri da aka sanya masa wani takwara sabon maganin.

A cikin shakka daga likita far da muhimmanci a kiyaye a kula da tsarin sigogi na homeostasis (platelet ƙidaya, gwaje-gwaje na aikin aiki, APTT). The aikin ayyuka na hanta da kuma ya kamata a kai a kai da kuma kula kimanta a matsayin mai tsanani sabawa a cikin aikin da zai kara hadarin hemorrhagic diathesis.

Medicaments, wanda babban aiki sashi ne clopidogrel ( "Plagril" analogs), ba da shawarar ga wadanda suka sha wahala wani m tsokar zuciya infarction, a kalla a lokacin farko da 'yan makonni bayan farko. Likita kwararru ba da shawarar "Plagrilom" far idan haƙuri yana da m angina, tare da ischemic bugun jini a jijiyoyin zuciya kewaye tiyata.

Tare da wani adadin na taka tsantsan da ake bukata domin daukar wani magani ga mutane da nakasa a cikin aiki na kodan.

Don}-liyafar "Plagrila"?

"Plagril" (Allunan) umurci haramta marasa lafiya da hypersensitivity ko rashin ha} uri ga mutum main kuma karin gyara na medicament. Kada ku riƙi da miyagun ƙwayoyi a kowane cututtuka predisposing zuwa zub da jini (na ciki da kuma duodenal ulcers, hyperfibrinolysis, huhu daji da tarin fuka, da dai sauransu). A karfi tushe ga maras amfani "Plagrila" ne m hanta gazawar, hemorrhagic ciwo. Bugu da kari zuwa sama, an contraindicated shan magani ga mata masu ciki da masu jego. Ba don rubũta da miyagun ƙwayoyi zuwa yara a karkashin shekaru 18 da haihuwa.

shirye-shirye analogues

A pharmaceutical kasuwar yau, wani rukuni na kwayoyi antiplatelet jamiái ( "Plagril" ma'ana da abun ciki na babban aiki aka gyara) samuwa isasshe yadu. Fiye da 3 dozin kwayoyi - antiplatelet jamiái da wannan aiki sashi (clopidogrel) da kuma a cikin wannan sashi (75 MG). Baya daga Rasha masana'antun sarrafa antiplatelet Indian pharmaceutical kamfanonin, Enterprises Hungary, Isra'ila, Malta, France.

"Dr. Reddies dakunan gwaje-gwaje" "Plagril" kanta samar da wani India kamfanin. By misalin, za mu iya hada Faransa "Plavix" German "Clopidogrel ratiopharm," Hungarian "Clopidogrel-Richter," Isra'ila "Clopidogrel Teva," Maltese "Liporel" Macedonian "Listab 75". "Zilt" za a iya ware daga cikin shahararrun da kuma yadu a bukatar Rasha jamiái.

"Zilt" - Rasha "Plagril"

Babban aiki abu na cikin shirye-shiryen "Zilt" ( "Plagril" a cewa shi ne cikakken m) ne clopidogrel. Magani nasa ne da rukuni na antiplatelet jamiái. A farko kashi (for "Zilt" - 400 MG) bayan 2 hours bayan gwamnati slows platelet tari. Kamar yadda "Plagril", "Zilt", azurta samun 50-100 MG da rana za ta samar da matsakaicin warkewa sakamako bayan 4-7 kwanaki.

Medicament metabolized a cikin hanta. A abun da ke ciki na jini na aiki metabolites aka gano. Aƙalla 50% "Zilta" excreted da kodan, sauran 46% a cikin kwanaki 5 bayan mai karɓa za a janye ta cikin hanji.

Alamomi ga yin amfani da "Zilta" ne guda kamar yadda a "Plagrila": rigakafin thrombus samuwar a marasa lafiya jurewa tsokar zuciya infarction, ischemic bugun jini ko wahala daga cuta jijiya patency.

mabukaci ra'ayi

Kamar kowane miyagun ƙwayoyi, da "Plagrila", yana da kyau kima na masu amfani da, duka biyu tabbatacce kuma korau reviews. Akwai marasa lafiya a wanda da miyagun ƙwayoyi da aka nada don lura da angina da kuma nuna kansa da mai matukar tasiri miyagun ƙwayoyi. Tare da yin amfani da hare-haren da ya faru ko a duk, ko su zama da yawa kasa. Tare da abokan ciniki a cikin kimantawa da magunguna "Plagril" martani daga likitoci.

Duk da haka, za ka iya saduwa da kuma lura game da illa ya sa ta yin amfani da magani. Wasu mutane rubuta game da bayyanar bruises, wasu a fili bayyana anemia. Sun kasance marasa lafiya da kuma aukuwa na tsanani da ciwon kai, da kuma sosai daban-daban kwatance cuta a cikin narkewa kamar tsarin. Rare, amma za a iya ji a kan m, a kan aiwatar da samun "Plagrila" ciki miki ko duodenal miki.

A general, shi ya kamata a ce cewa miyagun ƙwayoyi "Plagril 'umarnin don amfani wurin sa a matsayin tsanani isasshen magani ba dace da dukkan magunguna. Yana da wani fairly m jerin contraindications, zai iya sa da yawa daga gefen effects daga wani iri-iri da kuma tsarin gabobin. Uncontrolled amfani iya ta isa korau (da kuma wani lokacin babu ja) aqibar kiwon lafiya na haƙuri.

A ƙarshe daga duk na sama ne kai-bayyananne. "Plagril" domin lura da hanya ya kamata a nada da halartar likita. Kuma mafi wani zaɓi na lura da wannan magani - a wani asibiti da kuma karkashin kulawa na manyan masana. Kawai a cikin wannan hali mu iya fatan for da kyau sakamako daga cikin miyagun ƙwayoyi da kadan hadarin illa.