Medicine 'MabThera'. Umarnin don amfani

A category na anticancer kwayoyi hada da miyagun kwayoyi "MabThera". Description medicament yana nuna ikon musamman kisa to transmembrane antigen ba a 95% na wadanda ba Hodgkin ta lymphomas, B-cell form. Active bangaren - rituximab.

Medicine "MabThera". Umarnin: shaidar

Magani wajabta B-cell ba Hodgkin ta lymphoma:

- himioustoychivoy ko maimaita, CD20-tabbatacce tare da low-sa ko follicular.

- follicular uku ko hudu mataki a hade tare da jiyyar cutar sankara a marasa lafiya ba a baya fallasa da magani.

- bayan da follicular mayar da martani ga shigar da far a matsayin goyon baya nufin;

- CD20-tabbatacce B-manyan-a hade tare da sara jiyyar cutar sankara makirci.

Na nufin "MabThera" manual shawarar da kullum lymphocytic cutar sankarar bargo :

- a hade tare da jiyyar cutar sankara a marasa lafiya da suke yi ba, an hõre misali magani.

- maimaita ko himioustoychivom a hade tare da jiyyar cutar sankara.

Medicament nuna manya da wani aiki nau'i na rheumatoid amosanin gabbai a hade tare da medicament "MTX" rashin lokacin amfani hypersensitive martani ko warkewa regimens.

contraindications

Na nufin "MabThera" wa'azi ba da shawarar idan kun kasance hypersensitive.

Tsanaki dole ne a nuna a lokacin da gudanarwa kwayoyi ga marasa lafiya da arrhythmia, angina, congestive zuciya rashin cin nasara, ko rashin jini, thrombocytopenia, neutropenia, COPD (saboda yiwuwar faru na bronchospasm).

illa

A da ake ji da miyagun ƙwayoyi "MabThera" Ko sa tashin zuciya, ciwon mara, amai. A korau bayyananen kuma sun hada da orthostatic hypotension, arrhythmia, tachycardia, bradycardia, hanawa na koda aiki, na gefe edema, zafi a cikin kirji da lumbosacral kashin baya yanki. Da miyagun ƙwayoyi "MabThera" zai iya sa gefe neuropathy, neuritis, drowsiness ko rashin barci, agitation ko ciki, da damuwa, wani rauni, juwa ko jiri, zafi a kai. M events dauke su wani rashin lafiyan dauki. A korau halayen lokacin amfani da miyagun ƙwayoyi "MabThera" umarnin su ne rhinitis, pharyngeal edema ko harshe, shortness na numfashi, bronchospasm, itchy fata, low jiki nauyi, da rashin lafiya na dandano, tremors, jin sanyi, zazzabi, zafi a cikin wuyansa yankin da kuma a site na ƙari sarrafawa, ci gaban herpetic cututtuka.

sashi

Da miyagun ƙwayoyi ne gudanar da jinkirin igiyar jini jiko. Lokacin da monotherapy aka yi amfani da sau daya a mako a 375 MG ga hudu makonni. A farko kudi na farko gwamnatin 50mg / h. Kara a cikin matsakaicin (400 MG / h) dole ne sauka a hankali kudi.

tsõratar

Talatin zuwa sittin minti kafin gwamnati shawarar premedication (shiri) tare da analgesics da antihistamine kwayoyi.

A lokacin far, da kuma a cikin watanni goma sha biyu bayan kammala mata na haihuwa dole ne amfani da m maganin hana haihuwa.

Antihypertensive kwayoyi ya kamata a daina amfani da a kalla goma sha biyu sa'o'i kafin gwamnatin da miyagun ƙwayoyi "MabThera".

Ba kafa inganci da kuma aminci daga cikin miyagun ƙwayoyi a yara.

A cikin shirye-shiryen "MabThera" comments daga masana kagaggun tabbatacce. Haka kuma, a cikin shakka daga gudanar da bincike, an gano cewa, nan da nan ganawa da miyagun ƙwayoyi a matsayin monotherapy, kazalika da m amfani da shi a matsayin wani goyon baya nufin shekara biyu lowers yiwuwar worsening da follicular lymphoma.