Imidazoliletanamid pentandiovoy acid: pharmacological mataki, aikace-aikace, analogues

Idan likitan ka ya ya kamu da wani "kwayar cutar", yana nufin cewa kana bukatar ka bi da shi yadda ya kamata. A fairly babban rukuni na mu yan'uwanmu 'yan ƙasa yi imani da cewa maganin rigakafi - mafi kyau magani ga dukkan cututtuka. Abin takaici, shi ne wani kuskure cutar da yawa fiye da da ainihin rashin lafiya. Maganin rigakafi ne kawai aiki da kwayan cututtuka, amma su ne m da ƙwayoyin cuta.

Ta yaya miyagun ƙwayoyi ayyuka?

Akwai quite babban yawan kwayoyi tare da antiviral aiki. Daya daga cikin na kowa abubuwa da cewa suna da wannan dukiya - shi imidazoliletanamid pentandiovoy acid.

Shi ne aiki da pathogens iri na mura A da B, adenovirus, parainfluenza da kuma taimaka tare da numfashi syncytial cutar kamuwa da cuta.

Wannan aiki fili yana da musamman inji na mataki. Yana damuarn da haihuwa aiwatar a ƙwayoyin cuta kwaya lokaci mataki da kuma retards da hijirarsa daga sabuwar dauke da kwayar cutar wakili daga cytoplasmic yanayi tsakiya Kwayoyin.

Har ila yau imidazoliletanamid pentandiovoy acid da aka rayayye da hannu a cikin mutum rigakafi da tsarin, samar da wani modulating sakamako. The abu qara jini interferon abun ciki zuwa matakin na physiological kullum. shi ma stimulates aiwatar da α-, γ-interferonproduktsii leukocytes, sakamakon shi a daidai Jihar wadannan ayyuka.

Bincike na aiki abu ya nuna cewa imidazoliletanamid pentandiovoy acid inganta cikin ƙarni na cytotoxic lymphocytes mataki. Haka kuma, shi qara yawan NK-T-jamiái da cewa suna da yarda da juna, ikon hallaka Kwayoyin canza kama da ƙwayoyin cuta, kazalika da yi kai tsaye a kan pathogens.

A amfani ne da gaban da miyagun ƙwayoyi da anti-mai kumburi Properties. Suna bayar da suppressing samar da cytokines profile, kazalika da rage a cikin ayyuka na enzyme myeloperoxidase.

warkewa sakamako

Imidazoliletanamid pentandiovoy acid, reviews daga waxanda suke da kyau, na gaba ya nuna da warkewa sakamako a lura da SARS da kuma mura:

• Ya rage tsawon na febrile tsari.
• Rage bayyanar cututtuka na maye (dizziness, zafi, wani rauni).
• Rage catarrhal manifestations.
• Minimizes rikitarwa wannan rashin lafiya.
• Rage lokaci na rashin lafiya.

Kwayoyi da imidazoliletanamidom pentandiovoy acid

A kantin magani za a iya samu da wadannan formulations dauke da imidazoliletanamid pentandiovoy acid:

• "Vitaglutam" powders.
• "Ingavirin" a cikin nau'i na capsules.
• "Dicarbamine" kwayoyi.

contraindications

Kamar yadda da wani magani imidazoliletanamid pentandiovoy acid - wani magani wanda dole ne a gudanar da halartar likita. Wannan pharmaceutical samfurin yana da contraindications, ciki har da:

• A lokacin daukar ciki da kuma lactation.
• Yara har zuwa shekaru 18 years.
• Hypersensitivity miyagun ƙwayoyi aka gyara.

Side effects daga magani dauke da aka bayyana a aiki abu za a iya bayyana a cikin nau'i na rashin lafiyan dauki.

Wannan sakamako da aka bayar cewa mutum yana da wani mutum ji na ƙwarai to imidazoliletanamidu pentandiovoy acid ko karin abubuwa, wanda wani bangare ne na miyagun ƙwayoyi.

aminci

Wasu mutane kokarin kauce wa yin amfani da wannan magani, da imani da cewa imidazoliletanamid pentandiovoy acid - shi ne wani kwayoyin. Wannan ra'ayi ne kuskure, tun da wannan aiki abu farfado kawai antiviral aiki. Kira ingancin deprives shi daga duk illa cewa ne muhimmi antimicrobial miyagun ƙwayoyi profile. Da miyagun ƙwayoyi yana da wani immunotoxic, carcinogenic, mutagenic ko allergenic mataki ba tare da irritating narkewa kamar fili ba rage haihuwa aiki yana da wani embryotoxic ko teratogenic sakamako.

Alama ta wani m high aiki na da kwayoyi da aka hada da imidazoliletanamid pentandiovoy acid analogs wanda aka dauka da baki. Su suna hanzari tunawa a cikin gastrointestinal fili da kuma ake ko'ina rarraba a gabobin da kyallen takarda. Tuni bayan rabin awa bayan ingestion na magani sashi kai ta matsakaicin maida hankali a cikin jini da kuma gudanar da 37 hours. A tsawon lokaci da magani aka 5 days. Kowane gwamnati da miyagun ƙwayoyi a Jump na da abun ciki a cikin jini, wanda rage-rage sannu a hankali lokacin da rana. Da miyagun ƙwayoyi a jikin mutum ba metabolized fitarwa canzawa da kodan da kuma hanjinsu.

fasalin liyafar

Yana da muhimmanci a kiyaye da sashi regimen da miyagun ƙwayoyi. Imidazoliletanamid pentandiovoy acid analogs halin kamar guda shawarwarin domin amfani, ya kamata a cinye baki sau daya a rana, a wani adadin na 90 MG na tsawon 5-7 kwanaki, ko da kuwa ci abinci.

A peculiarity wannan magani mai pharmaceutical wakili ne cewa mafi girma yadda ya dace shi ne cimma a lokacin da ba bayan ganowa na farko alamun cutar a cikin na farko na kwana biyu.

"Vitaglutam" - tushen daga cikin rukuni na antiviral jamiái

A tarihin da miyagun ƙwayoyi ke mayar da 70s na karshe karni. Yana da aka ɓullo da ta shahara Rasha likita pulmonologist Alexander Chuchalin. A medicament qunshi a matsayin babban aiki sashi imidazoliletanamid pentandiovoy acid. "Vitaglutam" da aka gabatar a karkashin cinikin sunan "Dicarbamine" har 2008. Manufarsa shine cewa, a ta da hematopoiesis tsari a cikin marasa lafiya da suke halartar far lura da ciwon daji.

A shekarar 2009, Adam ya gamu da mummunan cutar kamuwa da cuta - swine mura, ko da A / H1N1. A wannan lokaci, "Vitaglutama 'cigaban sun sosai dacewa. Aleksandr Chuchalin, wanda shi ne a wancan lokacin manyan likita na Rasha Federation, yanke shawarar gwada da ya halitta da swine mura cutar da kuma ya samu nasara sakamakon. Ya ce cewa cikin gida samfurin, wanda dogara ne a kan imidazoliletanamid pentandiovoy acid, "Vitaglutam" ya nuna ya fi inganci da kamuwa da cuta karaya fiye da American Pharmaceutical samfurin "Tamiflu". Ya aka rayayye batutuwa a cikin kwayar genome, sai ta halakar da ita.

New Life "Vitaglutam" miyagun ƙwayoyi "Ingavirin"

Chuchalin samarwa Gennady Onishchenko, shugaban tsafta likita na Rasha Federation, ya yi amfani da sabuwar dabara kamar yadda wani tasiri kayan aiki da magani daga swine mura. A sakamakon gwajinsu da miyagun ƙwayoyi da aka gudanar, a cikin abin da ta tabbatar da ingancinta game da daban-daban kwayar cututtuka. Da miyagun ƙwayoyi da aka bai da wani sabon sunan "Ingavirin" da kuma aka rajista a cikin littãfi daga cikin rukuni na antiviral da immunostimulatory kwayoyi.

Da zarar wannan samfurin ne a Pharmaceutical kamfanin "Valenta" ya tafi a kan sale, shi da aka hukuma da shawarar da ma'aikatar Lafiya a matsayin magani ga swine mura da kuma fara buga records na shahararsa a tsakanin yawan jama'a. Saboda haka, za mu iya ce game da daidaici "Dicarbamine" - imidazoliletanamid pentandiovoy acid - "Vitaglutam", da cewa shi ne, a gaskiya, wanda kuma wannan magani.

Shi ne ya kamata a lura da cewa "Ingavirin" ya tafi sayarwa a 2008 sanya ba tare da cikakken gwajinsu. Tare da taimako Onishchenko a shekarar 2009 kara gwajinsu a dakin gwaje-gwaje beraye aka shirya. Har ila yau a wannan taron, ya samu halartar game da 100 marasa lafiya halarci. Bisa ga sakamakon da binciken da tawagar ya kai ga Chuchalin kammala da cewa "Ingavirin" a cikin ta farko 48 hours daga farkon kamuwa da cuta nuna mun gwada high dace cuta pathogens. Its mataki da aka nuna a cikin akan rage febrile lokaci, ragewa yawan guba a dakin gwaje-gwaje dabbobi da marasa lafiya da kuma rage catarrhal manifestations.

Saboda haka, babu wani dalili to tunani game da imidazoliletanamid pentandiovoy acid da cewa shi ne gunki - ingancinta an tabbatar asibiti.

"Dicarbamine" a yau

A halin yanzu, duk uku kwayoyi a kan tushen imidazoliletanamida pentandiovoy acid kudi ne wanzu da kuma ake armashi kamar yadda takwarorinsu da juna.

"Dicarbamine" shawarar don amfani da marasa lafiya da gaban m siffofin maruran. Bugu da kari ga babban aiki sashi, shi yana dauke da madara da sukari, talc, dankalin turawa, sitaci, magnesium stearate, colloidal bayani daga silicon dioxide da stearic acid.

"Dicarbamine" yana da wadannan warkewa effects:

• Hanzari daga neutrophil bambantawa da kuma aikin maturation.
• Gematoprotektsiya da myelosuppressive jiyyar cutar sankara.
• Rage aukuwar kuma mataki na mai guba neutropenia, leukopenia iyakance.

Wannan shiri ne da shawarar a yi amfani tsakanin darussa na jiyyar cutar sankara.

Ingancinta riga na fili bayan 21-28 kwanaki na kullum gwamnatin Allunan.

A guda kashi na magani - 100 MG (1 kwamfutar hannu) - dauka 5 kwanaki kafin a fara jiyyar cutar sankara da kuma ci gaba a ko'ina cikin magani. "Dicarbamine" yana da dukiya ya inganta da kuma tsawanta da mataki na anticancer cytotoxic kwayoyi, don rage mai guba sakamakon cyclophosphamide da platinum tushen kwayoyi, da kuma haifar da al'ada matakai na hematopoiesis.