Beta-agonists: description, mataki jerin kwayoyi

Kowane miyagun ƙwayoyi yana nufin wasu pharmacological kungiyar. Wannan na nufin cewa wasu kwayoyi da wannan inji na mataki, alamomi da kuma illa. Daya daga cikin manyan Pharmaceutical kungiyoyin - wannan shi ne wani beta-adrenergic agonists. Wadannan kwayoyi suna yadu amfani da magani na numfashi da kuma zuciya da jijiyoyin jini pathologies.

Mene ne A-agonists?

Beta-agonists - wani rukuni na na'urorin kiwon lafiya da aka yi amfani da magani na cututtuka daban-daban. A cikin jiki, an ɗaure su takamaiman rabe dake a cikin m tsoka na bronchi, mahaifa, zuciya da kuma jijiyoyin bugun gini kyallen takarda. Irin wannan hulda sa wani ruri daga beta Kwayoyin. A sakamakon da kunnawa da daban-daban physiological tafiyar matakai. Bayan dauri na B-agonists zuwa rabe stimulates samar da nazarin halittu jamiái, kamar dopamine da adrenaline. Wani sunan ga wadannan mahadi - beta-agonists. Major effects daga gare - hanzari na zuciya rate, ta ƙara jini da kuma inganta Bronchial watsin.

Beta-agonists: mataki a cikin jiki

Beta-agonists kasu kashi V1- da B2-adrenergic agonists. Rabe na wadannan abubuwa ne a cikin kayan ciki. Bayan dauri ga beta-agonists kai ga kunnawa da yawa tafiyar matakai a cikin jiki. Akwai da wadannan effects na B-agonists:

1. Kara cardiac automaticity da watsin kyautata.
2. Karuwan zuciya rate.
3. Hanzari daga lipolysis. A amfani, B1-agonists bayyana a cikin jini free m acid wanda su ne kayayyakin da Lalacewar triglycerides.
4. Karuwan jini. Wannan sakamako ne saboda da ruri na renin-angiotensin-aldosterone tsarin (RAAS).

Don da aka jera canje-canje a cikin jiki take kaiwa zuwa dauri na agonists B1 rabe. Suna located a cikin zuciya tsoka, jini, adipose nama da juxtaglomerular na'ura na koda Kwayoyin.

B2 rabe suna located a cikin bronchi, mahaifa, kwarangwal tsoka, tsakiya m tsarin. Bugu da kari, su ne zuciya da jini. Beta-2-agonists sa da wadannan effects:

1. Inganta Bronchial watsin. Wannan sakamako ne saboda da shakatawa na m tsoka.
2. Hanzari daga glycogenolysis a cikin tsokoki. A sakamakon kwarangwal tsoka sauri kuma mafi rage.
3. A shakatawa na myometrium.
4. Hanzari glycogenolysis a hanta Kwayoyin. Wannan take kaiwa zuwa ƙãra jini sugar matakan.
5. Karuwan zuciya rate.

Abin da kwayoyi ne a rukuni na B-agonists?

Doctors sau da yawa rubũta beta-agonists. Kwayoyi na ga wannan pharmacological kungiyar, zuwa kashi takaice da kuma azumi-aiki da magunguna. Bugu da kari, ya zama ruwan dare kwayoyi kawai da zabe sakamako a kan wasu gabobin. Wasu kwayoyi aiki kai tsaye a kan V1- da v2-rabe. Mafi fi sanin magunguna daga cikin rukuni na beta-agonists ne kwayoyi "Salbutamol", "fenoterol", "Dopamine". A agonists amfani da magani na huhu da kuma cardiac cututtuka. Har ila yau, wasu daga cikinsu suna amfani da yanayin m kula naúrar (miyagun ƙwayoyi "Dobutamine"). Kadan na kowa kwayoyi a cikin wannan kungiya suna amfani da gynecological yi.

Nau'in beta-agonists: irin magunguna

Beta-agonists - wannan pharmacological kungiyar, wanda ya hada da babban yawan magunguna. Saboda haka, da suka kasu kashi da dama kungiyoyin. Nau'in B-agonists sun hada da:

1. Non-zabe beta-adrenergic agonists. Wannan kungiyar hada da miyagun kwayoyi "ortsiprenalina" da "Isoprenaline".
2. Zababben B1-agonists. Suna amfani da cardiology da m kula da zabe. Wakilai na wannan kungiyar da kwayoyi ne "Dobutamine" da "Dopamine".
3. Zababben beta-2-agonists. Wannan kungiyar hada magunguna amfani ga cututtuka na numfashi tsarin. Bi da bi, da zabe B2 agonist kasu kashi short-aiki da kwayoyi, da kuma kwayoyi da ciwon dogon m sakamako. Na farko da kungiyar hada magunguna "fenoterol", "terbutaline" "Salbutamol" da "hexoprenaline". Long-aiki kwayoyi - wani magani "Formoterol", "Salmeterol" da "indacaterol."

Alamomi A-agonists

Alamomi ga yin amfani da B-agonists dogara a kan irin miyagun ƙwayoyi. Beta-agonists ne ba zabe mataki yanzu da wuya amfani. Tun da farko, an amfani da su bi wasu iri arrhythmias, worsening cardiac madugu, Bronchial asma. Yanzu likitoci fi son rubũta zabe B-agonists. Su amfani ne da cewa suna da nisa m illa. Bugu da kari, zabe kwayoyi sauƙin amfani, kamar yadda kawai shafi wasu gabobin.

Alamomi ga B1-agonists nufin:

1. M zuciya rashin cin nasara.
2. A tura da wani etiology.
3. Durkushe.
4. Decompensated zuciya lahani.
5. Da wuya - ischemic cututtukan zuciya da tsanani digiri.

B2-agonists gudanar a Bronchial fuka, na kullum obstructive na huhu cuta. A mafi yawan lokuta, wadannan kwayoyi an yi amfani da fom na aerosols. Wani lokaci magani "fenoterol" da ake amfani a gynecological yi wa rage aiki, da kuma hana ashara. A wannan yanayin, da miyagun ƙwayoyi ne gudanar intravenously.

A wasu lokuta, B-agonists suna contraindicated?

Ya kamata a tuna da cewa miyagun ƙwayoyi kungiyar A beta-agonists da yawan contraindications da illa. Wannan Gaskiya ne, a cikin wadanda ba zabe agonists. Side effects na wadannan kwayoyi - .. Shin ci gaban hyperglycemia, reshe tremors, zuciya kari cuta, tsakiya m tsarin zumudi, da dai sauransu Beta-1 agonists ne m kwayoyi, saboda haka an yi amfani ne kawai a lokuta da gaggawa bukatar. Suna contraindicated a marasa lafiya tare da wani tarihi na irin Pathology: na ramin zuciya arrhythmia, subaortic stenosis, pheochromocytoma. Har ila yau, sun ba za a iya amfani da cardiac tamponade.

B2-agonists ana contraindicated a cikin wadannan lokuta:

1. Rashin ha} uri ga beta-agonists.
2. Pregnancy wuya ta zub da jini, placental abruption, wa'adi ashara.
3. Yara a karkashin 2 years old.
4. Kumburi tafiyar matakai a myocardium, cardiac arrhythmias.
5. Ciwon sukari mellitus.
6. Aortic stenosis.
7. Hauhawar jini.
8. M zuciya rashin cin nasara.
9. Thyrotoxicosis.

Medicament "Salbutamol": umarnin don amfani da

Drug "Salbutamol" yana nufin B2-agonists na gajeren mataki. Ana amfani da a cikin ciwo na Bronchial shãmakacẽwa. Mafi sau da yawa amfani da aerosols for 1-2 allurai (0.1-0.2 MG). Yara fĩfĩta yi da inhalation via wani nebulizer. Akwai kuma kwamfutar hannu tsari da miyagun ƙwayoyi. A sashi na manya ne 6-16 MG da rana.

"Salbutamol": miyagun ƙwayoyi farashin

Da miyagun ƙwayoyi amfani da monotherapy a m asma. Idan haƙuri yana da matsakaici ko matsananci mataki na cuta, tsawo amfani da kwayoyi (beta-agonists dogon-addashin). Kuma sune far da Bronchial asma. ta amfani da miyagun ƙwayoyi "Salbutamol" domin saurin taimako na kai hare-hare na breathlessness. A farashin da miyagun ƙwayoyi ne daga 50 zuwa 160 rubles dangane da manufacturer da kashi dauke a cikin vial.